News tagged with tau tangles
Genetic markers ID second Alzheimer's pathway
Researchers at Washington University School of Medicine in St. Louis have identified a new set of genetic markers for Alzheimer's that point to a second pathway through which the disease develops.
Alzheimer's disease & dementia
Apr 04, 2013 |
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Brain-imaging tool and stroke risk test help identify cognitive decline early
UCLA researchers have used a brain-imaging tool and stroke risk assessment to identify signs of cognitive decline early on in individuals who don't yet show symptoms of dementia.
Neuroscience
Apr 03, 2013 |
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Tau transmission model opens doors for new Alzheimer's, Parkinson's therapies
Injecting synthetic tau fibrils into animal models induces Alzheimer's-like tau tangles and imitates the spread of tau pathology, according to research from the Perelman School of Medicine at the University of Pennsylvania ...
Neuroscience
Mar 15, 2013 |
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Transmission of tangles in Alzheimer's mice provides more authentic model of tau pathology
Brain diseases associated with the misformed protein tau, including Alzheimer's disease and frontotemporal lobar degeneration with tau pathologies, are characterized by neurofibrillary tangles (NFTs) comprised ...
Neuroscience
Jan 15, 2013 |
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Neurons die in Alzheimer's because of faulty cell cycle control before plaques and tangles appear
The two infamous proteins, amyloid-beta (Aβ) and tau, that characterize advanced Alzheimer's disease (AD), start healthy neurons on the road to cell death long before the appearance of the deadly plaques and tangles by working ...
Alzheimer's disease & dementia
Dec 17, 2012 |
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New hope for treating Alzheimer's Disease: A role for the FKBP52 protein
New research in humans published today reveals that the so-called FKBP52 protein may prevent the Tau protein from turning pathogenic. This may prove significant for the development of new Alzheimer's drugs and for detecting ...
Alzheimer's disease & dementia
Mar 20, 2012 |
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Cancer drug improves memory in mouse model of Alzheimer's disease
A compound that previously progressed to Phase II clinical trials for cancer treatment slows neurological damage and improves brain function in an animal model of Alzheimer's disease, according to a study ...
Alzheimer's disease & dementia
Mar 13, 2012 |
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Untangling the mysteries of Alzheimer's
One of the most distinctive signs of the development of Alzheimer's disease is a change in the behavior of a protein that neuroscientists call tau. In normal brains, tau is present in individual units essential to neuron ...
Neuroscience
Feb 02, 2012 |
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Alzheimer's: French scientists focus on key target
French scientists said on Tuesday that lack of a key brain protein was linked to Alzheimer's, a finding that threw up a tempting target for drugs to fight the disease.
Neuroscience
Jan 24, 2012 |
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Imaging technique IDs plaques, tangles in brains of severely depressed older adults
Depression is one of the most common mental disorders in the elderly, but little is known about the underlying biology of its development in older adults.
Psychology & Psychiatry
Nov 08, 2011 |
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Single traumatic brain injury may prompt long-term neurodegeneration
Years after a single traumatic brain injury (TBI), survivors still show changes in their brains. In a new study, researchers from the Perelman School of Medicine at the University of Pennsylvania suggest that Alzheimer's ...
Neuroscience
Jul 18, 2011 |
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Weight loss after gastric bypass surgery reduces expression of Alzheimer's genes
Obesity is a risk factor for Alzheimer's disease, but weight loss due to bariatric surgery may reduce the risk of this common dementia, a new study suggests. The results will be presented Sunday at The Endocrine Society's ...
Medical research
Jun 06, 2011 |
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