How transcription factors work together in cancer formation
A new study co-authored by University of Colorado Cancer Center researcher Srinivas Ramachandran, Ph.D., shows how DNA segments known as enhancers function in cells.
Apr 14, 2021
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A new study co-authored by University of Colorado Cancer Center researcher Srinivas Ramachandran, Ph.D., shows how DNA segments known as enhancers function in cells.
Apr 14, 2021
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Preclinical research from VCU Massey Cancer Center published recently in the Proceedings of the National Academy of Sciences shows that the combination of two existing drugs can exploit the metabolic 'hunger' of a particularly ...
Mar 30, 2021
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Although the development of secondary cancerous growths, called metastasis, is the primary cause of death in most cancers, the cellular changes that drive it are poorly understood. In a new study, published in Genome Biology, ...
Mar 29, 2021
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A large team of researchers affiliated with a host of institutions in Europe and the U.S. has found a gene that plays a critical role in natural killer cell differentiation. In their paper published in the journal Science ...
Many genetic variants have been found to have a linkage with genetic diseases, but the understanding of their functional roles in causing diseases are still limited. An international research team, including a biomedical ...
Feb 24, 2021
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In chronic infections, the immune system can become exhausted. Ludwig-Maximilians-Universitaet (LMU) in Munich researchers have looked into how this works.
Feb 12, 2021
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Transcription factors—proteins that regulate gene expression—play critical roles in cell fate decisions and are frequent targets of mutation in a variety of human cancers. Understanding how transcription factors contribute ...
Feb 5, 2021
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How do cis-regulatory genome elements regulate gene expression, what are the critical components involved, and can we therapeutically target them? By investigating how corepressors modulate enhancers and silencers during ...
Jan 27, 2021
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Genetics has made huge strides over the past 20 years, from the sequencing of the human genome to a growing understanding of factors that turn genes on and off, namely transcription factors and the DNA "enhancer" sequences ...
Dec 22, 2020
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Over two million babies, children, and adults in the United States are living with congenital heart disease—a range of birth defects affecting the heart's structure or function. Now, researchers at Gladstone Institutes ...
Dec 14, 2020
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