The metabolic enzyme IL4I1 (Interleukin-4-Induced-1) promotes the spread of tumor cells and suppresses the immune system. This was discovered by scientists at the German Cancer Research Center (DKFZ) and the Berlin Institute ...
Aug 20, 2020
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Progress against DIPG, a fatal childhood brain tumor, is usually a game of inches. Studies that hint at even small gains are cause for celebration.
Aug 13, 2020
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A new study by researchers at the University of Kentucky identifies a novel function of the enzyme spermine synthase (SMS) to facilitate colorectal cancer growth.
Jul 15, 2020
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An enzyme that blocks the metabolic processes that contribute to the rapid growth and spread of liver cancer has been discovered, according to a study by researchers at Sanford Burnham Prebys and Weill Cornell Medicine. The ...
Jun 26, 2020
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Radiolabeled molecules, so-called radiotracers, help nuclear physicians to detect and precisely target tumors, which often develop due to pathological changes in metabolic processes. Using positron emission tomography, a ...
Apr 6, 2020
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Using human lung cancer cells, UT Southwestern researchers have uncovered how cells in general modulate their energy consumption based on their surroundings and, furthermore, how cancer cells override those cues to maximize ...
Feb 24, 2020
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Colon cancer cells deficient in p53, one of the most important control proteins in cell growth, activate a particular metabolic pathway to adapt to the lack of oxygen and nutrients inside the tumor. Statins, which are often ...
Dec 12, 2019
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A compound developed by Johns Hopkins researchers that blocks glutamine metabolism can slow tumor growth, alter the tumor microenvironment and promote the production of durable and highly active anti-tumor T cells.
Nov 8, 2019
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Researchers at the UCLA Jonsson Comprehensive Cancer Center have identified a new drug delivery pathway that may help stop tumor growth and keep cancer from coming back in mice. In the preclinical study, the team found that ...
Sep 25, 2019
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Cancer researchers are setting their sights on a new kind of cancer treatment that targets the tumor's surrounding environment, called the tumor microenvironment, in contrast to targeting the tumor directly.
Sep 4, 2019
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