SPACE, RF ablation combo safe and effective for lung cancer
(HealthDay)—For unresectable lung tumors, the combination of segmental pulmonary arterial chemoembolization (SPACE) and percutaneous radiofrequency (RF) ablation helps achieve better local tumor progression ...
Cancer
May 15, 2013 |
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Newly identified tumor suppressor provides therapeutic target for prostate cancer
Scientists at Sanford-Burnham Medical Research Institute (Sanford-Burnham) have identified how an enzyme called PKCζ suppresses prostate tumor formation. The finding, which also describes a molecular chain ...
Cancer
Apr 01, 2013 |
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Preclinical study identifies 'master' proto-oncogene that regulates ovarian cancer metastasis
Scientists at The University of Texas MD Anderson Cancer Center have discovered the signaling pathway whereby a master regulator of cancer cell proteins – known as Src – leads to ovarian cancer progression when exposed ...
Cancer
Jan 29, 2013 |
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Compound stimulates tumor-fighting protein in cancer therapy
A compound that stimulates the production of a tumor-fighting protein may improve the usefulness of the protein in cancer therapy, according to a team of researchers.
Cancer
Feb 06, 2013 |
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Taming physical forces that block cancer treatment
A Massachusetts General Hospital research team has identified factors that contribute to solid stress within tumors, suggesting possible ways to alleviate it, and has developed a simple way to measure such pressures.
Cancer
Sep 20, 2012 |
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Some cancer mutations slow tumor growth
A typical cancer cell has thousands of mutations scattered throughout its genome and hundreds of mutated genes. However, only a handful of those genes, known as drivers, are responsible for cancerous traits ...
Cancer
Feb 04, 2013 |
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Lack of oxygen in cancer cells leads to growth and metastasis
(Medical Xpress)—It seems as if a tumor deprived of oxygen would shrink. However, numerous studies have shown that tumor hypoxia, in which portions of the tumor have significantly low oxygen concentrations, ...
Cancer
Sep 13, 2012 |
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Team finds biological indicator of aggressive, recurrent forms of prostate cancer
(Medical Xpress)—In a study to decipher clues about how prostate cancer cells grow and become more aggressive, Johns Hopkins urologists have found that reduction of a specific protein is correlated with the aggressiveness ...
Cancer
Aug 27, 2012 |
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Transition in cell type parallels treatment response, disease progression in breast cancer
A process that normally occurs in developing embryos – the changing of one basic cell type into another – has also been suspected of playing a role in cancer metastasis. Now a study from Massachusetts General Hospital ...
Cancer
Jan 31, 2013 |
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Two-pronged approach to immune activation could lead to vaccines that effectively shut down tumor expansion
Tumor cells often express proteins that set them apart from their healthy neighbors. These very same proteins can also help the immune system to recognize and destroy the cancer. Several research groups and ...
Cancer
Apr 26, 2013 |
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Researchers engineer 'protein switch' to dissect role of cancer's key players
Researchers at the University of North Carolina at Chapel Hill School of Medicine have "rationally rewired" some of the cell's smallest components to create proteins that can be switched on or off by command. ...
Cancer
Apr 10, 2013 |
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DNA test shows promise in guiding advanced breast cancer care
(HealthDay)—An experimental blood test could help show whether women with advanced breast cancer are responding to treatment, a preliminary study suggests.
Cancer
Mar 13, 2013 |
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Molecular 'two-way radio' directs nerve cell branching and connectivity
(Medical Xpress)—Working with fruit flies, Johns Hopkins scientists have decoded the activity of protein signals that let certain nerve cells know when and where to branch so that they reach and connect ...
Neuroscience
Jan 07, 2013 |
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Researchers link new molecular culprit to breast cancer progression
(Phys.org)—Johns Hopkins researchers have uncovered a protein "partner" commonly used by breast cancer cells to unlock genes needed for spreading the disease around the body. A report on the discovery, published November ...
Cancer
Nov 25, 2012 |
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Unexpected toughness may mark out cancer cells in the blood
(Medical Xpress)—A surprising discovery about the physical properties of cancer cells could help improve a new diagnostic approach – a liquid biopsy – that detects, measures, and evaluates cancer cells ...
Cancer
Dec 04, 2012 |
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