A Cleveland Clinic-led team of scientists and physicians have discovered that the immune checkpoint protein VISTA can directly turn off tumor-fighting T-cells during immunotherapy and resist treatment.
May 17, 2024
0
22
Activated T cells that carry a certain marker protein on their surface are controlled by natural killer (NK) cells, another cell type of the immune system. In this way, the body presumably curbs destructive immune reactions.
May 3, 2024
0
27
Metabolic diseases like obesity can increase the risk of developing liver cancer, research has shown. But how one disease predisposes to the other is unclear. In a new study, Yale researchers uncovered a key role played by ...
Apr 26, 2024
0
3
Using artificial intelligence, Ludwig Cancer Research scientists have developed a powerful predictive model for identifying the most potent cancer-killing immune cells for use in cancer immunotherapies.
May 7, 2024
0
33
Scientists from Scripps Research have enhanced an existing immunotherapy by removing the sugar coating surrounding solid tumors—such as in melanoma, breast, and prostate cancer—so T cells can more effectively kill tumor ...
May 1, 2024
0
33
Researchers at the National Cancer Institute-designated Montefiore Einstein Comprehensive Cancer Center (MECCC) have shown that a breakthrough therapy for treating blood cancers can be adapted to treat solid tumors—an advance ...
May 8, 2024
0
11
A team of researchers led by Dr. Hirotsugu Oda at the University of Cologne's CECAD Cluster of Excellence for Aging Research has discovered the role a specific protein complex plays in certain forms of immune dysregulation. ...
Apr 29, 2024
0
18
Women's health is often talked about in terms of major, life-altering events like pregnancy and menopause. A new study from Cold Spring Harbor Laboratory (CSHL) underscores the importance of considering everyday occurrences' ...
May 2, 2024
0
12
Researchers at Texas Children's Cancer Center and the Center for Cell and Gene Therapy at Baylor College of Medicine, Texas Children's Hospital and Houston Methodist have published results of a Phase I clinical trial of a ...
Apr 24, 2024
0
39
Starving out tumor cells may be a promising therapy for treatment-resistant lung cancer, according to a new study published in Science Advances.
May 6, 2024
0
26
