A new approach to treating type I diabetes? Gut cells transformed into insulin factories
A study by Columbia researchers suggests that cells in the patient's intestine could be coaxed into making insulin, circumventing the need for a stem cell transplant. Until now, stem cell transplants have been seen by many ...
Genetics
Mar 11, 2012 |
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Autoimmune disease—retraining white blood cells
Symptoms of an autoimmune disease disappeared after a team of scientists retrained the white blood cells. This method is extremely promising for treating diseases such as type I diabetes and multiple sclerosis.
Immunology
Dec 17, 2012 |
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Parasitologist espouses using parasitic worms for treatment of autoimmune diseases
(Medical Xpress)—Doctor Joel Weinstock, a parasitologist at Tufts Medical Center in a commentary piece published in the journal Nature, describes work that he and colleagues have been involved in that focuses on studyi ...
Immunology
Nov 08, 2012 |
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Research sheds light on important role of autophagy, or self-eating cells, in developing new anti-inflammatory therapies
Research just carried out in the Immunology Research Centre, led by Dr James Harris, based in the School of Biochemistry and Immunology, Trinity College Dublin, shows that the process of autophagy regulates the production ...
Medical research
Oct 24, 2012 |
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Genetic clues to causes of primary biliary cirrhosis
Researchers have newly identified three genetic regions associated with primary biliary cirrhosis (PBC), the most common autoimmune liver disease, increasing the number of known regions associated with the ...
Genetics
Sep 09, 2012 |
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Antibodies reverse type 1 diabetes in new immunotherapy study
Scientists at the University of North Carolina School of Medicine have used injections of antibodies to rapidly reverse the onset of Type I diabetes in mice genetically bred to develop the disease. Moreover, ...
Diabetes
Jul 05, 2012 |
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Study shows how the breakup of two proteins interferes with the immune system
Autoimmune diseases, such as Type I diabetes and rheumatoid arthritis, are caused by an immune system gone haywire, where the body's defense system assaults and destroys healthy tissues. A mutant form of a ...
Immunology
Mar 18, 2012 |
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New 'smart' nanotherapeutics can deliver drugs directly to the pancreas
A research collaboration between the Wyss Institute for Biologically Inspired Engineering at Harvard University and Children's Hospital Boston has developed "smart" injectable nanotherapeutics that can be programmed to selectively ...
Medical research
Jan 12, 2012 |
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Researchers find molecule that prevents Type 1 diabetes in mice
Researchers at the University of Colorado School of Medicine have found a specific molecule that can prevent the development of type 1 diabetes in mice and has a similar effect on human cells from diabetic patients.
Medical research
Nov 01, 2011 |
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New mouse model may lead to new therapies for degenerative diseases
Most degenerative diseases begin with a gradual loss of specific cell types that progresses, eventually leading to symptoms. For example, in type I diabetes, hyperglycemia commonly develops when approximately 80 percent of ...
Medical research
May 16, 2011 |
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Researchers report islet cell advancement increases impact on transplantation
A study published in the current issue of Cell Transplantation (21:8), now freely available on-line, reports that a team of researchers in South Korea have successfully engineered islet cell clusters (ICCs) that will improv ...
Medical research
Nov 27, 2012 |
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Study: Post-menopausal women with diabetes at greater risk of breast cancer
(Medical Xpress)—Women with type II diabetes are nearly 30 per cent more likely to get breast cancer, according to results of a comprehensive review published in the British Journal of Cancer today (Frida ...
Cancer
Sep 14, 2012 |
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Short-term intestinal parasite infection triggers specific cytokines that can prevent the development of type 1 diabetes
(Medical Xpress) -- Short-term infection with intestinal worms may provide long-term protection against type I diabetes (TID), suggests a study conducted by William Gause, PhD, and colleagues at the University of Medicine ...
Immunology
Jul 19, 2012 |
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Xenotransplantation as a therapy for type 1 diabetes: Pig beta cells show great promise in an animal model
Transplantation of a whole pancreas or isolated insulin-producing beta cells are the only therapy to cure type I diabetes. However, the shortage of organ donors limits this approach to only few patients. LMU researchers have ...
Diabetes
Apr 23, 2012 |
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Insulin therapy may help repair atherosclerotic lesions in diabetic patients
New research reveals that insulin applied in therapeutic doses selectively stimulates the formation of new elastic fibers in cultures of human aortic smooth muscle cells. These results advance the understanding of the molecular ...
Diseases, Conditions, Syndromes
Jan 09, 2012 |
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