Evidence of host adaptation of avian-origin influenza A virus
The connection between human avian-origin influenza A (H7N9) virus infection and environmental sources of the virus were determined based on clinical data, epidemiology, and virological characteristics of the three early ...
Diseases, Conditions, Syndromes
May 15, 2013 |
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Proteins expressed by human cytomegalovirus mapped
(Medical Xpress)—A new study in the US and Germany has added to our understanding of the human cytomegalovirus (HCMV) and how it manipulates the cells it infects.
Medical research
Nov 23, 2012 |
4.8 / 5 (5) |
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Researchers show how cells' DNA repair machinery can destroy viruses
A team of researchers based at Johns Hopkins has decoded a system that makes certain types of immune cells impervious to HIV infection. The system's two vital components are high levels of a molecule that ...
Medical research
Jan 21, 2013 |
4.3 / 5 (6) |
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Retrovirus in the human genome is active in pluripotent stem cells
A retrovirus called HERV-H, which inserted itself into the human genome millions of years ago, may play an important role in pluripotent stem cells, according to a new study published in the journal Retrovirology by scient ...
Medical research
Jan 23, 2013 |
5 / 5 (9) |
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Discovery could lead ways to prevent herpes spread
(Medical Xpress) -- Herpesviruses are thrifty reproducers -- they only send off their most infectious progeny to invade new cells. Two Cornell virologists recently have discovered how these viruses determine ...
Medical research
Sep 14, 2011 |
5 / 5 (4) |
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When body clock runs down, immune system takes time off
It's been said that timing is everything, and that may be particularly true when it comes to the ability to fight off disease. New research published by Cell Press in the February issue of the journal Immunity shows that t ...
Immunology
Feb 16, 2012 |
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New research sheds light on the molecular mechanisms by which a virus contributes to cancer
Hepatocellular carcinoma (HCC) is the third leading cause of cancer deaths worldwide and is associated with exposure to hepatitis B virus (HBV). Patients carrying the virus have a 100-fold greater risk of ...
Cancer
Aug 29, 2012 |
5 / 5 (3) |
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Early antiretroviral treatment reduces viral reservoirs in HIV-infected teens
A study led by University of Massachusetts Medical School professor and immunologist Katherine Luzuriaga, MD, and Johns Hopkins Children's Center virologist Deborah Persaud, MD, highlights the long-term benefits of early ...
HIV & AIDS
Mar 04, 2013 |
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Field guide to the Epstein-Barr virus charts viral paths toward cancer
Researchers from The Wistar Institute and Memorial Sloan-Kettering Cancer Center (MSKCC) have teamed to publish the first annotated atlas of the Epstein-Barr virus genome, creating the most comprehensive ...
Medical research
Aug 23, 2012 |
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Mutation drives viral sensors to initiate autoimmune disease
A new study uses a mouse model of a human autoimmune disease to reveal how abnormal regulation of the intracellular sensors that detect invading viruses can lead to autoimmune pathology. The research, published online on ...
Immunology
Jan 26, 2012 |
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In cancer, an embryonic gene-silencing mechanism gone awry
There are some genes that are only activated in the very first days of an embryo's existence. Once they have accomplished their task, they are shut down forever, unlike most of our genes, which remain active throughout our ...
Genetics
Oct 04, 2012 |
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'Junk DNA' can sense viral infection
Once considered unimportant "junk DNA," scientists have learned that non-coding RNA (ncRNA) — RNA molecules that do not translate into proteins — play a crucial role in cellular function. Mutations in ncRNA are ...
Medical research
Apr 24, 2012 |
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Mouse model could help identify viral vectors that may cause tumors
Investigators at Nationwide Children's Hospital have identified a mouse model that could help evaluate the risk that viral vectors used in gene therapy might promote tumor formation as a side-effect. The study appears in ...
Cancer
Oct 26, 2012 |
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Discovery could lead to faster diagnosis for some chronic fatigue syndrome cases
For the first time, researchers have landed on a potential diagnostic method to identify at least a subset of patients with chronic fatigue syndrome (CFS), a complex disorder with no known definitive cause or cure.
Diseases, Conditions, Syndromes
Nov 14, 2012 |
5 / 5 (1) |
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First-ever integrative 'Omics' profile lets scientist discover, track his diabetes onset
Geneticist Michael Snyder, PhD, has almost no privacy. For more than two years, he and his lab members at the Stanford University School of Medicine pored over his body's most intimate secrets: the sequence of his DNA, the ...
Genetics
Mar 15, 2012 |
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