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Alzheimer's disease & dementia news
Neuroscience
Loss of empathy is a key problem in people with frontotemporal dementia—here's what's happening in the brain
Frontotemporal dementia has gained significant attention in recent years after the family of actor Bruce Willis announced in 2023 that he had been diagnosed with the condition. A year later, it was revealed that US chat show ...
12 hours ago
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Genetics
AI helps unravel a cause of Alzheimer's disease and identify a therapeutic candidate
A new study found that a gene recently recognized as a biomarker for Alzheimer's disease is actually a cause of it, due to its previously unknown secondary function. Researchers at the University of California San Diego used ...
Apr 25, 2025
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Brain's 'blue spot' key to healthy aging, early Alzheimer's detection
In a demographically diverse sample of healthy people, Cornell researchers found dramatic changes over the human lifespan in the brain's "blue spot"—a tiny region involved in cognition and believed to be the first affected ...
Apr 24, 2025
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Even light exercise could help slow cognitive decline in people at risk of Alzheimer's
Researchers at the University of California San Diego and Wake Forest University have found that both low and moderate-high intensity exercise could be valuable tools in the fight against Alzheimer's.
Apr 24, 2025
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Immune dysfunction and inflammation found to play significant roles in Alzheimer's disease
Brain tissue analysis of an animal model has revealed the potential role of immune system dysfunction in the onset and progression of Alzheimer's disease (AD).
Apr 24, 2025
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Dementia care: Are terms of endearment like 'sweetheart' comforting or condescending?
In the emotionally complex world of dementia care, communication is more than just what we say—it's how we say it. Terms of endearment like "darling," "my lovely," and "sweetheart" are often used by health care staff with ...
Apr 24, 2025
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Clinical trials are the next step for testing vaccine against Alzheimer's-promoting tau protein
University of New Mexico Health Sciences researchers hope to launch human clinical trials in their quest for a vaccine to prevent the buildup of pathological tau—a protein in the brain associated with Alzheimer's dementia.
Apr 23, 2025
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New clues as to why drugs are effective for Alzheimer's disease
A team of scientists including UCL researchers has tested four anti-amyloid Alzheimer's therapeutics to find out how the drugs bind to toxic amyloid beta protein to tackle the disease.
Apr 23, 2025
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Empathy might be retained in Alzheimer's disease, finds a new study
People with Alzheimer's disease may retain their ability to empathize, despite declines in other social abilities, finds a new study led by University College London (UCL) researchers.
Apr 23, 2025
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Metabolic syndrome linked to increased risk of young-onset dementia
Having a larger waistline, high blood pressure and other risk factors that make up metabolic syndrome is associated with an increased risk of young-onset dementia, according to a study published in Neurology.
Apr 23, 2025
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US dementia costs to exceed $780 billion this year
The total economic burden of Alzheimer's disease and related dementias in the United States will reach $781 billion this year, according to new USC-led research.
Apr 23, 2025
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Hearing loss in older adults linked to nearly one-third of dementia cases
A multi‑institution research team including Columbia, Vanderbilt, Johns Hopkins and others, report that nearly one in three new dementia cases in older adults is associated with hearing loss, based on statistical modeling ...
Virtual singing brings connection and joy to isolated older adults, study finds
American philosopher and psychologist William James once said, "I don't sing because I'm happy. I'm happy because I sing." Now, a new Northwestern University Feinberg School of Medicine study has found that even when singing ...
Apr 22, 2025
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Getting treatment for high blood pressure may reduce chances of developing dementia
Reducing high blood pressure substantially lowers the risk of dementia and cognitive impairment without dementia, according to the results of a phase 3 clinical trial involving almost 34,000 patients, published in Nature ...
Apr 21, 2025
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Alzheimer's risk factors that can impact cognition in adults as young as 24 revealed
A new study from Columbia University Mailman School of Public Health and the Columbia Butler Aging Center suggests that risk factors and biomarkers related to Alzheimer's disease are associated with cognition much earlier ...
Apr 21, 2025
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Programmable microglia target and clear toxic proteins linked to Alzheimer's disease
A new way to deliver disease-fighting proteins throughout the brain may improve the treatment of Alzheimer's disease and other neurological disorders, according to University of California, Irvine scientists. By engineering ...
Apr 21, 2025
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Global telemedicine therapy for dementia shows benefit in clinical trial
For people living with primary progressive aphasia (PPA), a rare, early-onset neurodegenerative dementia that predominantly affects language abilities, something as simple as ordering their favorite meal at a drive-thru can ...
Apr 18, 2025
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Modulating the brain's immune system may curb damage in Alzheimer's
New research suggests that calming the brain's immune cells might prevent or lessen the damaging inflammation seen in Alzheimer's disease. The study points to the key role of the hormone and neurotransmitter norepinephrine, ...
Apr 17, 2025
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Gene 'reversal' in fruit flies points to new hope for Alzheimer's treatment
A study published in The American Journal of Human Genetics by researchers at Baylor College of Medicine and the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Children's Hospital provides solutions ...
Apr 17, 2025
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Mouse model reveals how the Icelandic mutation protects against Alzheimer's disease
RIKEN researchers have demonstrated the protective effects of a specific genetic mutation against Alzheimer's disease in animals for the first time. This could eventually lead to the development of new ways to treat the neurodegenerative ...
Apr 17, 2025
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Five reasons why young-onset dementia is often missed
Around 57 million people worldwide have dementia. While most cases of dementia are diagnosed in older adults, about 7% of cases occur in people under 65. This number may be even higher as young-onset dementia continues to ...
Apr 17, 2025
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Hereditary Alzheimer's: Blood marker for defective neuronal connections rises early
Individuals with a genetic predisposition to Alzheimer's disease show altered blood levels indicating damaged neuronal contacts as early as 11 years before the expected onset of dementia symptoms. This is evident in the levels ...
Apr 16, 2025
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EU approves sale of new Alzheimer's drug, with conditions
The European Commission said Wednesday that it had given formal approval for Leqembi, a long-awaited new treatment for early-stage Alzheimer's disease, to be sold in the EU under strict conditions.
Apr 16, 2025
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How do age, sex, hormones and genetics affect dementia biomarkers in the blood?
A new study has found important clues about the roles age, sex, hormonal changes and genetics play in how certain biomarkers for dementia are expressed in the blood. The study was published online in Neurology.
Apr 16, 2025
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Menopause at an early age can exacerbate cognitive decline
A team of researchers from the Tohoku University Graduate School of Medicine and Tokyo Metropolitan Institute of Medical Science found that women who entered menopause before the age of 40 had worse cognitive outcomes than ...
Apr 16, 2025
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