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Archive
22/05/2024

Archive: 22/05/2024

Sweet move: A modified sugar enhances antisense oligonucleotide safety and efficacy for treating CNS disease

Researchers have found that a newly developed modified sugar increases the efficacy and safety of antisense oligonucleotides designed to treat central nervous system disease.

May 22, 2024

0

14

Sewage overflows linked to increase in gastrointestinal illnesses

During extreme rain or rapid snowmelt, the high volume of water that enters sewer systems can cause untreated sewage to flow into waterways in US cities that have combined wastewater and stormwater sewer systems, including ...

May 22, 2024

0

1

Immune-checkpoint inhibitors protect bone by promoting osteogenesis, exploratory study shows

Immune checkpoint inhibitors (ICIs), widely employed anticancer agents, have been found to impact bone turnover, potentially conferring a protective effect on bone through the promotion of osteogenesis. These surprising findings ...

May 22, 2024

0

19

Researchers develop new method to remove blood cells in leukemia patients while building new blood system

Researchers have developed an approach to "deleting" a blood system affected by leukemia while simultaneously building up a new, healthy system with donor blood stem cells. Writing in the journal Nature, the team reports ...

May 22, 2024

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63

Century-old vaccine found to protect type 1 diabetics from infectious diseases

In new research, investigators at Massachusetts General Hospital (MGH) show that the 100-year-old Bacillus Calmette-Guérin (BCG) vaccine, originally developed to prevent tuberculosis, protects individuals with type 1 diabetes ...

May 22, 2024

0

72

New tool can detect tiny protein clumps associated with neurodegenerative disorders

The clumping of proteins is at the root of a wide range of neurodegenerative disorders that affect the brain, such as Alzheimer's and dementia. Researchers at the University of Copenhagen have developed a new tool that can ...

May 22, 2024

0

25

Urban gardening may improve human health—research subjects benefit from microbial exposure

A collaborative study between the University of Helsinki, Natural Resources Institute Finland and Tampere University demonstrated that a one-month indoor gardening period increased the bacterial diversity of the skin and ...

May 22, 2024

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83

Stroke genetics: Independent HTRA1 mechanisms increase risk, shows study

Cardiovascular diseases, including stroke and coronary artery disease are among the leading causes of death worldwide. Classical risk factors include age, personal lifestyle, and pre-existing conditions, but genetic predisposition ...

May 22, 2024

0

7

To hunt for better malaria vaccines, researchers turn to machine learning

Anti-malaria drugs have been a central component of a global public health effort that saw a 44% drop in the deadly mosquito-borne disease from 2000 to 2019, but progress has stalled as the parasites that cause malaria gain ...

May 22, 2024

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6

New strain of vaccinia virus can induce immunogenic cell death in tumors

Vaccinia viruses are therapeutic tools with different biomedical applications depending on the susceptibility characteristics. For example, the strain called MVA (modified vaccinia Ankara), which is unable to replicate in ...

May 22, 2024

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