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Arthritis & Rheumatism news
Arthritis & Rheumatism
Inhibiting a master regulator of aging regenerates joint cartilage in mice
An injection that blocks the activity of a protein involved in aging reverses naturally occurring cartilage loss in the knee joints of old mice, a Stanford Medicine-led study has found. The treatment also prevented the development ...
Nov 27, 2025
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Arthritis & Rheumatism
Why certain arthritis drugs don't work in rheumatoid arthritis
Cedars-Sinai investigators may have figured out why certain immunosuppressive treatments don't work well in rheumatoid arthritis. In a study published in Science Immunology, scientists trace the problem to specific changes ...
Nov 26, 2025
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Both total and partial knee replacements deliver lasting benefits at 10 years, clinical trial finds
New research from a randomized clinical trial provides the strongest long-term evidence yet comparing partial (PKR) and total (TKR) knee replacements for patients with osteoarthritis. Published in The Lancet Rheumatology, ...
Nov 19, 2025
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Enzyme provides promising path to degenerative joint diseases cure
Degenerative joint diseases like osteoarthritis and intervertebral disk degeneration are conditions that affect millions of people worldwide, leading to pain and reduced mobility. These diseases remain incurable because current ...
Nov 13, 2025
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New points to consider in treatment-resistant psoriatic arthritis
Some people with psoriatic arthritis (PsA) may have a disease that is difficult to manage (D2M) or does not respond to treatment. EULAR—The European Alliance of Associations for Rheumatology—has released new evidence-based ...
Oct 30, 2025
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New genetic marker could improve prediction of severe gout drug reactions in US patients
A newly identified genetic marker may significantly improve the ability to predict life-threatening reactions to the gout medication allopurinol in U.S. patients.
Oct 29, 2025
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Study finds improvement in knee pain with exercise and physical therapy
People with a meniscal tear and osteoarthritis prescribed home exercises with or without physical therapy reported substantial improvements in knee pain, according to a new study led by Mass General Brigham researchers.
Oct 29, 2025
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SGLT-2 inhibitors tied to lower risk for autoimmune rheumatic diseases in adults with type 2 diabetes
Sodium-glucose cotransporter-2 (SGLT-2) inhibitors are associated with a reduced risk for autoimmune rheumatic diseases compared with sulfonylureas among adults with type 2 diabetes, according to a study published online ...
Oct 23, 2025
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Simple screening tool can help uncover underdiagnosed back condition, study finds
For millions of people living with back pain, the cause is often elusive. One underrecognized culprit is axial spondyloarthritis (axSpA)—a form of inflammatory arthritis that primarily affects the spine and sacroiliac joints ...
Oct 23, 2025
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Why so many pro soccer players develop osteoarthritis
A new paper finds that retired UK male professional soccer players who reported foot or ankle injuries during their careers were more likely to develop osteoarthritis in retirement. Retired players treated routinely with ...
Oct 22, 2025
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Muscle wasting reversed in patients with rheumatoid arthritis
Patients with rheumatoid arthritis increased their leg muscle volume when treated with an anti-rheumatic drug, offering new hope for improved muscle health.
Oct 16, 2025
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Customizable finger brace toggles between stiff and flexible for easier recovery
A friend's struggles with arthritis and the finger braces used to manage it inspired research by a Carnegie Mellon University student that could make it easier for patients to follow rehabilitation plans, speed up recovery ...
Oct 15, 2025
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Walking, cycling and swimming are likely the best exercises for knee osteoarthritis
For patients with knee osteoarthritis, aerobic activities such as walking, cycling, or swimming are likely to be the best exercise for improving pain, function, gait performance, and quality of life, finds a study published ...
Oct 15, 2025
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SGLT-2 diabetes drugs linked to lower risk of autoimmune diseases
Sodium-glucose cotransporter-2 (SGLT-2) inhibitors used to treat type 2 diabetes are associated with an 11% lower risk of autoimmune rheumatic diseases, such as rheumatoid arthritis and lupus, compared with another group ...
Oct 15, 2025
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Arthritis pain rising: How state policies matter
New research from The University of Texas at Arlington shows that differences in state welfare policies are linked to rising arthritis-related joint pain across much of the U.S.
Oct 15, 2025
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AI predicts future X-rays to help osteoarthritis patients and their doctors see what's coming
An AI system that can predict what a patient's knee X-ray will look like a year in the future could transform how millions of people with osteoarthritis understand and manage their condition, according to research by the ...
Oct 14, 2025
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Joint pain or osteoarthritis? Exercise could be the first line of treatment
Stiff knees, aching hips and the slow grind of chronic joint pain are often accepted as an unavoidable part of getting older. But while osteoarthritis is the world's most common joint disease, experts say the way we treat ...
Oct 10, 2025
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Study finds tailored exercise program feasible for adults over 80 with osteoarthritis
A new NDORMS study has found that a tailored exercise program for people aged 80 years and older with hip and/or knee osteoarthritis and other long term health conditions is both practical and acceptable, paving the way for ...
Oct 9, 2025
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New treatment for psoriatic arthritis shows promising results in early trial
A new treatment for a debilitating inflammatory condition which affects joints and skin has shown promising early results in an international clinical trial of more than 200 patients worldwide.
Oct 7, 2025
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Gene linked to rheumatic disease controls cell movement
A team of researchers at Karolinska Institutet, together with colleagues from Linköping University, has uncovered the function of a gene called DIORA1 (FAM167A), previously linked to autoimmune rheumatic diseases such as ...
Sep 29, 2025
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Low-dose radiation therapy offers substantial relief to people with painful knee osteoarthritis
A single course of low-dose radiation therapy may provide a safe and effective alternative treatment option for people with painful knee osteoarthritis according to a new randomized, placebo-controlled clinical trial.
Sep 28, 2025
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Seven-year study reveals rheumatoid arthritis begins long before symptoms, opening door to prevention
Scientists have discovered that rheumatoid arthritis (RA) doesn't start when the pain begins. It silently starts years earlier. RA is a debilitating autoimmune disease that causes painful joint inflammation and damage. The ...
Sep 24, 2025
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Self-guided online program improves quality of life in rheumatoid arthritis, psoriatic arthritis and lupus
Patients with rheumatoid arthritis, psoriatic arthritis, and systemic lupus erythematosus frequently face anxiety and depression along with chronic physical symptoms. Reported rates of depression range from 15% to 24% and ...
Analysis isolates population aging as primary driver of musculoskeletal disorders
Novel research shows that in approximately one third of countries and territories worldwide, population aging was the largest contributor to the growing burden of musculoskeletal disorders from 1990 to 2021.
Sep 16, 2025
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Tirzepatide found to be more cost-effective than semaglutide in patients with knee osteoarthritis, obesity
A microsimulation model was used to evaluate the cost-effectiveness of two glucagon-like peptide-1 receptor agonists (GLP1RAs), semaglutide and tirzepatide, for patients with osteoarthritis and obesity compared with usual ...
Sep 15, 2025
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