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Arthritis & Rheumatism

Study offers potential for early diagnosis and therapeutic intervention for rheumatoid arthritis

Currently, there are no cures for rheumatoid arthritis (RA), which affects 40,000 people in Ireland. The disease costs an estimated $22,000 per patient, per year with an overall cost to the health system of ~$608 million. ...

Arthritis & Rheumatism

AI chatbots rival doctors in accuracy for back pain advice, study finds

A new study reveals that artificial intelligence chatbots, such as ChatGPT, may be almost as effective as consulting a doctor for advice on low back pain.

Arthritis & Rheumatism

Study shows AFL players' hip issues begin in early career

Researchers from La Trobe University studied 58 pain-free male Australian Football League (AFL) draftees, finding that nearly half showed hip joint changes on Magnetic Resonance Imaging (MRI) and 20% had a particular hip ...

Arthritis & Rheumatism

Study uncovers key factors in myositis-induced muscle weakness

A study has shed new light on the mechanisms behind idiopathic inflammatory myopathies (myositis), a group of systemic autoimmune disorders known for causing severe muscle weakness, fatigue, and increased mortality.

Arthritis & Rheumatism

Machine learning helps identify rheumatoid arthritis subtypes

A machine-learning tool created by Weill Cornell Medicine and Hospital for Special Surgery (HSS) investigators can help distinguish subtypes of rheumatoid arthritis (RA), which may help scientists find ways to improve care ...

Arthritis & Rheumatism

Surprising mechanism of lupus kidney damage identified

A Berlin-led research team has uncovered critical regulators of severe kidney damage in patients with lupus, an autoimmune disorder affecting an estimated five million people worldwide, most of whom are young women. A small, ...

Arthritis & Rheumatism

Should I stop running if my knee hurts?

The most common site for pain in recreational runners is the knee. For some, especially older runners, the pain can be a symptom of osteoarthritis. But does running worsen knee pain and osteoarthritis?

Arthritis & Rheumatism

Major savings possible with app-based osteoarthritis treatment

Osteoarthritis treatment conducted digitally via an app costs around 25% of what conventional care costs, according to a study from Lund University in Sweden published in the research journal PLOS ONE. The researchers have ...

Arthritis & Rheumatism

Timely detection of axial spondyloarthritis

A large European cross-sectional study has now examined which factors delay the diagnosis of axSpA. A major factor is the number and type of medical professionals who have assessed the patients.

Medical research

New approach to treating osteoarthritis advances

The study results revolve around the long-established idea that machines within animal and human cells turn the sugars, fats, and proteins we eat into energy used by the body's millions of cells. The molecule most used to ...

Arthritis & Rheumatism

Change isn't a good thing for Japanese rheumatoid arthritis patients

In many cases, a complex interplay between our genes and the environment governs whether or not we will develop a certain disease. Interestingly though, researchers are discovering that the genetic component of disease predisposition ...

Medications

Bone drug may be beneficial for knee osteoarthritis

Bisphosphonates (a class of drugs that prevent the loss of bone density and used to treat osteoporosis and similar diseases) appear to be safe and beneficial for osteoarthritis patients.

Arthritis & Rheumatism

Gout diagnoses rising worldwide

The prevalence of gout—a form of arthritis characterized by severe pain, redness, and tenderness in joints—increased across the world at an alarming rate from 1990 to 2017, according to an analysis published in Arthritis ...

Arthritis & Rheumatism

Rheumatoid arthritis linked to a lower risk of type 2 diabetes

A recent analysis of a US commercial insurance database found that adults with rheumatoid arthritis had a lower risk of developing type 2 diabetes than other individuals, including those with other types of arthritis.

Arthritis & Rheumatism

A quarter of arthritis cases linked to excess weight

A new Boston University School of Public Health (BUSPH) study shows that weight loss between early adulthood and midlife lowers arthritis risk, and found no evidence of any persistent risk of arthritis for people who were ...

Medications

Reducing corticosteroid use in rheumatoid arthritis

Is the long-term use of glucocorticoids essential in people with chronic inflammatory diseases such as rheumatoid arthritis, or can early discontinuation prevent characteristic side effects? How can these drugs be discontinued ...

Genetics

Stretches of repeating DNA predispose to systemic sclerosis

Systemic sclerosis is an autoimmune disorder that is characterized by excess deposition of connective tissue in the skin, lungs, kidneys and vessels, resulting in lung, heart and kidney dysfunction. In a new study, researchers ...

Arthritis & Rheumatism

Blood test could reveal when rheumatoid arthritis will strike

AThe cells, dubbed "PRIME cells," accumulate in the blood during the week prior to disease flare-ups, Howard Hughes Medical Institute Investigator Robert Darnell's team reports July 15, 2020, in the New England Journal of ...