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Arthritis & Rheumatism news

Genetics

Early skeleton map reveals how bones form in humans

The first "blueprint" of human skeletal development reveals how the skeleton forms, shedding light on the process of arthritis, and highlighting cells involved in conditions that affect skull and bone growth.

Arthritis & Rheumatism

Knee problems tend to flare up as you age—an orthopedic specialist explains available treatment options

Knee injuries are common in athletes, accounting for 41% of all athletic injuries. But knee injuries aren't limited to competitive athletes. In our everyday lives, an accident or a quick movement in the wrong direction can ...

Arthritis & Rheumatism

Unifying systemic juvenile idiopathic arthritis and Still's disease

The European Alliance of Associations for Rheumatology, in partnership with the Pediatric Rheumatology European Society (PReS), has developed new recommendations for the diagnosis and management of Still's disease, comprising ...

Cardiology

Early rheumatoid arthritis tied to hypertension

Patients with early rheumatoid arthritis (RA) have a high incidence of prevalent and incident hypertension, according to a study published online in the August issue of Rheumatology: Advances in Practice.

Arthritis & Rheumatism

Study finds 41% of people have 'creaky knees'

La Trobe researchers have discovered that almost half the population has "creaky knees" in a study investigating how common the problem is and what it means for the health of our knees.

Arthritis & Rheumatism

Exposure to inorganic dust increases risk of gout in women by 27%

The results of a study presented today at the Annual European Congress of Rheumatology (EULAR 2019) demonstrate that occupational exposure to inorganic dust is a previously unknown risk factor for gout and also confirm known ...

Arthritis & Rheumatism

Rheumatoid arthritis—can its onset be delayed or prevented?

Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disorder that leads to significant health issues as well as high treatment costs. In this themed issue of Clinical Therapeutics, experts review multiple aspects ...

Arthritis & Rheumatism

New option for treating active rheumatoid arthritis

In a large-scale, international study led by renowned rheumatologist Josef Smolen from the Department of Medicine III, a still-to-be-approved drug containing the selective janus kinase inhibitor upadacitinib has proved itself ...

Arthritis & Rheumatism

New psoriatric arthritis mouse model developed

Psoriatic arthritis (PsA) is a chronic inflammatory disease that can reduce mobility and agility in patients. PsA is known to increase the risk of type II diabetes. A recent study published in The FASEB Journal tested a novel ...

Arthritis & Rheumatism

Postoperative infection rate similar across biologics in RA

(HealthDay)—For patients with rheumatoid arthritis (RA) undergoing arthroplasty, the risk for postoperative infection is similar across biologics but is increased with glucocorticoid use, according to a study published ...

Medical research

Mast cells crucial to causing osteoarthritis

Stanford University School of Medicine scientists have definitively linked mast cells, a class of cells belonging to the immune system, to the development of osteoarthritis, one of the world's most common causes of pain and ...

Arthritis & Rheumatism

Adverse childhood experiences negatively impact adults with lupus

Adults with lupus who report having had adverse childhood experiences (ACEs), such as abuse, neglect and household challenges, report higher disease activity, depression and poorer overall health compared to those without ...

Arthritis & Rheumatism

A deep-dive into the impact of arthritis drugs on gene expression

A new computational framework has revealed key differences between four rheumatoid arthritis medications and their impact on biological pathways in mice. Niki Karagianni of Biomedcode Hellas SA, Greece, and colleagues present ...

Arthritis & Rheumatism

CDC: Prevalence of arthritis 22.8 percent in U.S. adults in 2017

(HealthDay)—The prevalence of arthritis was 22.8 percent in U.S. adults in 2017, with statewide variation in prevalence and in the prevalence of severe joint pain and physical inactivity among those with arthritis, according ...

Arthritis & Rheumatism

Rehabilitating knees

A tear of the anterior cruciate ligament in a knee isn't just painful in the moment—the injury also increases a patient's risk of developing osteoarthritis later.