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Laboratory medicine news

Machine learning model identifies heart failure with reduced ejection fraction using routine lab indicators

A 13-indicator routine laboratory model shows moderate discrimination for distinguishing heart failure with reduced ejection fraction (HFrEF), according to a study published online Aug. 9 in Frontiers in Cardiovascular Medicine.

New approach cuts sepsis diagnosis from days to hours

Sepsis, a life-threatening condition that stems from the body trying to fight off an infection, plagues more than 1.5 million patients a year in the U.S. alone, with one in three deaths recorded in hospitals attributed in ...

Wastewater may offer an early warning of pertussis outbreaks

Pertussis, or whooping cough, continues to cause periodic outbreaks worldwide and can be especially dangerous for infants who have not completed vaccination. Yet conventional surveillance depends on people seeking medical ...

Researchers find cold storage platelets safe and effective

A new study has found platelets kept in cold storage are as effective at treating bleeding and have a longer shelf life than platelets stored at room temperature. Dr. James Preuss and Dr. Warren Pavey, from The University ...

New rapid test could transform iron treatment worldwide

Iron deficiency is one of the world's most common nutritional disorders, affecting millions of women and children globally. Yet diagnosing it remains difficult in many low-resource settings, where access to laboratories and ...

Improving the diagnosis of primary aldosteronism

A simple new method based on the results of two studies from Christofer Juhlin's research group can make it easier to identify the underlying cause of a common form of high blood pressure and help predict who will benefit ...

Blood test may help guide treatment for metastatic melanoma

A blood test that measures how quickly tumor cells divide could in the future help doctors assess prognosis and select treatment strategies for patients with melanoma that has spread to other parts of the body. This is shown ...

ULTRA maps glioma margins in 3D within 30 minutes

One of the major challenges in glioma surgery is that tumor boundaries are often difficult to define. Diffuse gliomas can infiltrate surrounding brain tissue beyond what surgeons can see directly or what conventional imaging ...

Cell-free DNA could detect adverse events from immunotherapy

A noninvasive blood test to detect genetic material shed by tumors may help clinicians identify adverse events related to treatment with immune checkpoint inhibitor drugs, investigators at the Johns Hopkins Kimmel Cancer ...

Online tool detects drug exposure directly from patient samples

Doctors and researchers try to understand what medications a person has taken by asking patients directly or by looking at medical records. But this information is often incomplete. People may forget what they took, use over‑the‑counter ...

Simple urine test developed to screen bladder cancer

Researchers have discovered that analyzing specific patterns of cell-free DNA (cfDNA) fragmentation in a simple urine sample can effectively diagnose and stage bladder cancer, offering a much-needed alternative to invasive ...

Fibulin-5: A potential marker for liver fibrosis detection

When damage to the liver caused by alcohol or viral infections persists, liver fibrosis progresses and replaces tissue with collagen fibers. This is especially a risk in chronic hepatitis C patients, where liver fibrosis ...