Diseases, Conditions, Syndromes

Smart software detects early-stage esophageal cancer

Thanks to smart software doctors will soon be able to detect early signs of esophageal cancer in patients with so-called Barrett's esophagus. This is the result of research conducted by Amsterdam UMC, the Catharina Hospital ...

Obstetrics & gynaecology

Acid reflux drug is a surprising candidate to curb preterm birth

Lansoprazole, an over-the-counter acid reflux drug that is often taken by pregnant women, may be a promising therapy to reduce preterm birth, according to a computational drug repurposing study that also tested several of ...

Pediatrics

New paediatric care model produces positive results

An Australian pilot study involving 896 families has found that paediatricians embedded into GP clinics reduced emergency department referrals and unnecessary prescriptions. The program, run in north west Melbourne, also ...

Diseases, Conditions, Syndromes

Acid reflux affects nearly a third of US adults weekly

Gastroesophageal reflux disease (GERD), a digestive disorder that causes heartburn and other uncomfortable symptoms, may affect nearly a third of U.S. adults each week, and most of those who take certain popular medications ...

Diseases, Conditions, Syndromes

Got chronic heartburn? Easy does it during the Thanksgiving feast

(HealthDay)—The turkey, stuffing, cranberries, green bean casserole and mashed potatoes on the Thanksgiving table may look tempting, but if you have gastroesophageal reflux disease (GERD) you should proceed with caution, ...

Diseases, Conditions, Syndromes

Could your indigestion be GERD?

(HealthDay)—Heartburn. Millions of people suffer from it. But what exactly is it and, most important, could it actually be something serious?

Diseases, Conditions, Syndromes

Protein progression in Barrett's Esophagus disease

A study led by Nikhil Reddy, a second-year student at the Wright State University Boonshoft School of Medicine, has charted a protein's decline through the progression of Barrett's esophagus disease. The sickness, typically ...

Medications

Popular heartburn drugs may up odds of stomach bug

(HealthDay)—If you're one of the millions who rely on medications known as proton pump inhibitors for relief from heartburn, you may be at higher risk of illness from a stomach bug, new research suggests.

Medications

Two more heartburn meds recalled due to possible carcinogen

(HealthDay)—The U.S. Food and Drug Administration is adding to a list of recalled lots of popular heartburn medications—including generic forms of Zantac—because the pills might contain small amounts of a suspected ...

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Gastroesophageal reflux disease (GERD), gastro-oesophageal reflux disease (GORD), gastric reflux disease, or acid reflux disease is a chronic symptom of mucosal damage caused by stomach acid coming up from the stomach into the esophagus. A typical symptom is heartburn.

GERD is usually caused by changes in the barrier between the stomach and the esophagus, including abnormal relaxation of the lower esophageal sphincter, which normally holds the top of the stomach closed; impaired expulsion of gastric reflux from the esophagus, or a hiatal hernia. These changes may be permanent or temporary ("transient").

Another kind of acid reflux, which causes respiratory and laryngeal signs and symptoms, is called laryngopharyngeal reflux (LPR) or "extraesophageal reflux disease" (EERD). Unlike GERD, LPR is unlikely to produce heartburn, and is sometimes called silent reflux.

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