Diseases, Conditions, Syndromes

UAH nurses give tips for preventing Hepatitis, Hepatitis A

Hepatitis A is on the rise in Alabama. In December, the Alabama Department of Public Health sounded the alarm about a Hepatitis A (Hep A) outbreak in Jackson County, the north easternmost county in the state. Hep A is contracted ...

Medications

How does ecstasy kill?

MDMA (Methylenedioxymethamphetamine), commonly referred to as ecstasy, was manufactured as a potential pharmaceutical early last century. It had some limited use in the 1970s as a therapeutic aid in trauma treatment and in ...

Cancer

Many hepatitis infections go undiagnosed in cancer patients

Results from the largest study of hepatitis B and C and HIV infection prevalence in cancer patients show an alarmingly high rate of undiagnosed acute and chronic hepatitis B and C. Hepatitis B and C are serious but treatable ...

Diseases, Conditions, Syndromes

New therapeutic targets for kidney fibrosis emerge

Chronic kidney disease is a global health concern, affecting about 10 percent of the world's population—and increasing in prevalence. A final, common pathway in chronic kidney disease is fibrosis. Just as fibrosis—or ...

Diseases, Conditions, Syndromes

Cellular target may aid in drug therapies for acute liver failure

(Medical Xpress) -- New insights into the biological mechanisms that contribute to acute liver failure could help scientists better understand—and eventually treat—a broader spectrum of liver diseases, according ...

Diseases, Conditions, Syndromes

Researchers develop new approach to treat acute liver failure

Acute liver failure is a life-threatening disease, characterized by a sudden, massive death of liver cells. Unfortunately, few treatment options exist, especially for advanced-stage liver failure. As a last resort a liver ...

Genetics

Cause of acute liver failure in young children discovered

Acute liver failure is a rare yet life-threatening disease for young children. It often occurs extremely rapidly, for example, when a child has a fever. Yet in around 50 percent of cases it is unclear as to why this happens. ...

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Acute liver failure is the appearance of severe complications rapidly after the first signs of liver disease (such as jaundice), and indicates that the liver has sustained severe damage (loss of function of 80-90% of liver cells). The complications are hepatic encephalopathy and impaired protein synthesis (as measured by the levels of serum albumin and the prothrombin time in the blood). The 1993 classification defines hyperacute as within 1 week, acute as 8–28 days and subacute as 4–12 weeks. It reflects the fact that the pace of disease evolution strongly influences prognosis. Underlying etiology is the other significant determinant of outcome.

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