Cocktail proves toxic to leukemia cells
A combination of drugs that affect mitochondria—the power plants inside cells—may become the best weapons yet to fight acute myeloid leukemia, according to Rice University researchers.
Oct 31, 2019
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A combination of drugs that affect mitochondria—the power plants inside cells—may become the best weapons yet to fight acute myeloid leukemia, according to Rice University researchers.
Oct 31, 2019
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The key to treating one of the most common types of human leukemia may lie within mutations in a gene called FLT3, according to new research led by physician-scientists at the University of California, San Francisco (UCSF) ...
Apr 15, 2012
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A new study by the NYU Cancer Institute, an NCI-designated cancer center, sheds light on the origins of myeloid leukemia, a type of blood cancer that affects children and adults. The researchers discovered that novel mutations ...
May 12, 2011
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Researchers at University of California San Diego School of Medicine, Sanford Stem Cell Institute and Moores Cancer Center report that a late-stage, pre-clinical small molecule inhibitor, called rebecsinib, reverses malignant ...
Feb 16, 2023
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Monika McBride has acute myeloid leukemia, a life-threatening blood cancer that requires six months of intensive chemotherapy. Three days before her third treatment, however, a nurse called to cancel her appointment: Her ...
Aug 19, 2011
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(HealthDay)—A polygenic score derived from pharmacogenomic evaluation of cytarabine (ara-C) pathway can help personalize treatment for pediatric patients with acute myeloid leukemia (AML), according to a study published ...
Feb 1, 2022
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In a paper, "Epitope editing enables targeted immunotherapy of acute myeloid leukaemia," published in Nature, researchers at the Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, introduce a genetic ...
University of Georgia researchers, with colleagues from the University of Tokyo, have identified a new drug target for the two most common types of myeloid leukemia, including a way to turn back the most aggressive form of ...
May 17, 2017
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A group of researchers at Children's Hospital of Philadelphia (CHOP), in collaboration with Beam Therapeutics, have tested and developed an "off-the-shelf" chimeric antigen receptor T-cell (CART) using base editing, which ...
May 23, 2022
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An article published in the journal Nature Communications describes a specific metabolic adaptation in some patients with acute myeloid leukemia affected by tandem mutations in the FLT3 gene. The findings, which could shed ...
Jul 13, 2022
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