Medical research

Cracking 'virus code' could help fight cancer

Virus experts from Cardiff University's School of Medicine have uncovered, for the first time, how a virus known as Adenovirus type 26 (Ad26), which has been used effectively in a tamed form as a vaccine, can infect human ...

Oncology & Cancer

Genetically modified virus combats prostate cancer

Researchers at the São Paulo State Cancer Institute (ICESP) in Brazil have used a genetically manipulated virus to destroy tumor cells upon injection into mice with prostate cancer. The virus also made tumor cells more sensitive ...

Oncology & Cancer

Virologists harness adenovirus to kill breast cancer cells

With a $40,250 grant from the Lottie Caroline Hardy Charitable Trust Fund, researchers at Saint Louis University's Institute for Molecular Virology will study a small fragment of adenovirus as a possible future therapy for ...

HIV & AIDS

'New' human adenovirus may not make for good vaccines, after all

In recent years, scientists have studied the possibility of using engineered human adenoviruses as vaccines against diseases such as HIV, tuberculosis, and malaria. In this approach, adenoviruses, which commonly cause respiratory-tract ...

Medical research

Researchers find smallpox drug may also target adenovirus

Scientists at Saint Louis University have made two key discoveries that could lead to the first-ever human testing of a drug to target the adenovirus, which causes a number of severe upper-respiratory infections and is one ...

Diseases, Conditions, Syndromes

Adenoviruses may pose risk for monkey-to-human leap

Adenoviruses commonly infect humans, causing colds, flu-like symptoms and sometimes even death, but now UC San Francisco researchers have discovered that a new species of adenovirus can spread from primate to primate, and ...

Diseases, Conditions, Syndromes

Predicting the next eye pathogen; analysis of a novel adenovirus

The ongoing dance between a virus and its host distinctly shapes how the virus evolves. While human adenoviruses typically cause mild infections, recent reports have described newly characterized adenoviruses that can cause ...

Diseases, Conditions, Syndromes

Human adenovirus surveillance data IDs type patterns

(HealthDay)—Human adenovirus (HAdV) surveillance data can be used to determine patterns of circulation for individual HAdV types in the United States and to help with the recognition of outbreaks, according to a study published ...

Oncology & Cancer

Adenoviruses and the immune system join forces against cancer

Researchers of the Cancer Virotherapy Research Group of Bellvitge Biomedicine Research Institute (IDIBELL), led by Dr. Ramon Alemany, have developed an oncolytic virus capable of redirecting the patient's immune system against ...

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Adenoviruses are medium-sized (90–100 nm), nonenveloped (without an outer lipid bilayer) icosahedral viruses composed of a nucleocapsid and a double-stranded linear DNA genome. There are 57 described serotypes in humans, which are responsible for 5–10% of upper respiratory infections in children, and many infections in adults as well.

Viruses of the family Adenoviridae infect various species of vertebrates, including humans. Adenoviruses were first isolated in 1953 from human adenoids. They are classified as group I under the Baltimore classification scheme, meaning their genomes consist of double stranded DNA.

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