How does your brain talk with your arm? The body doesn't use English, or any other spoken language. Biomedical engineers are developing methods for decoding the conversation, by analyzing electrical patterns in the motor ...
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A mechanism for amyotrophic lateral sclerosis (ALS) development has been discovered at Umeå University, Sweden. The researchers report that proteins with a defect structure spread the deformation to other proteins. The discovery ...
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Four out of five people with motor neuron disease are likely to experience changes in their brain function, as well as impaired movement, research suggests.
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The Xrp1 protein appears to play an important role in the development of certain forms of ALS and dementia caused by a mutation in the FUS gene. This finding of Radboud University researchers was published on September 12th ...
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Few treatments exist for neurodegenerative diseases that progressively rob a person's ability to move and think, yet the results of a new study could potentially open additional approaches for exploration.
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(HealthDay)—The decision to overturn the End of Life Option Act has added stress and anxiety to terminally ill patients, including those with amyotrophic lateral sclerosis (ALS), according to a patient testimonial published ...
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Laboratory studies have shown the potential for patients with amyotrophic lateral sclerosis (ALS), who cannot move or speak, to communicate using a brain-computer interface (BCI). In the first study of independent in-home ...
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It's known as the disease that attacks the body but leaves the mind unaffected. But a new study shows that amyotrophic lateral sclerosis, also called ALS or Lou Gehrig's disease, does affect the mind, especially later in ...
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Protective proteins that mitigate the destruction of nerve cells after a stroke can be administered into the brain through the nose, as Heidelberg University researchers demonstrated using a mouse model. The team led by Prof. ...
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Nearly all major neurodegenerative diseases—from Alzheimer's to Parkinson's—are defined and diagnosed by the presence of one of four proteins that have gone rogue: tau, amyloid-beta (Aβ), alpha-synuclein (α-syn), or ...
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A City of Hope researcher has developed a stem cell model to assess possible treatments for a rare nervous system disorder that is in the same disease group as Alzheimer's disease, Parkinson's disease and amyotrophic lateral ...
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About 20,000 people in the United States are living with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease. The invariably fatal disease kills the nerve cells that control walking, eating and breathing. ...
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A class of cancer drugs called PARP inhibitors could be useful for treating and preventing brain disorders, including amyotrophic lateral sclerosis (ALS), also called Lou Gehrig's disease, and some forms of frontotemporal ...
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Approximately 2 to 3 percent of children suffer from a condition called strabismus, which is more commonly known as "lazy eye" or "crossed eyes." The majority of cases are thought to involve both genetic and environmental ...
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Neuroscientist Dr. David Vilchez and his team at CECAD, the University of Cologne's Cluster of Excellence for Aging Research, have made an important step toward understanding the mechanisms that cause the neurodegenerative ...
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Amyotrophic lateral sclerosis (ALS), also referred to as Lou Gehrig's disease in American English and Motor Neurone Disease in British English, is a form of Motor Neuron Disease caused by the degeneration of upper and lower neurons, located in the ventral horn of the spinal cord and the cortical neurons that provide their efferent input. The condition is often called Lou Gehrig's disease in North America, after the New York Yankees baseball player who was diagnosed with the disease in 1939. The disorder is characterized by rapidly progressive weakness, muscle atrophy and fasciculations, spasticity, dysarthria, dysphagia, and respiratory compromise. Sensory function generally is spared, as is autonomic and oculomotor activity. ALS is a progressive, fatal, neurodegenerative disease with most affected patients dying of respiratory compromise and pneumonia after 2 to 3 years; although some perish within a year from the onset of symptoms, and occasional individuals have a more indolent course and survive for many years.
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In the brain, as in business, connections are everything. To maintain cellular associates, the outer surface of a neuron, its membrane, must express particular proteins—proverbial hands that reach out and greet nearby cells. ...
In proof-of-concept experiments, University of Alabama at Birmingham researchers have highlighted a potential therapy for a rare but potentially deadly blood-clotting disorder, TTP. The researchers deliver this therapeutic ...
Researchers at Rensselaer Polytechnic Institute—led by Juergen Hahn, professor and head of biomedical engineering—are continuing to make remarkable progress with their research focused on autism spectrum disorder (ASD). ...
Most patients diagnosed with type 2 diabetes are treated with a "one-size-fits-all" protocol that is not tailored to each person's physiology and may leave many cases inadequately managed. A new study by scientists at the ...
Using an artificial intestine they created, researchers have shown that the microbiome can quickly adapt from the bacterial equivalent of a typical western diet to one composed exclusively of dietary fats. That adaptation ...
Researchers from Michigan State University College of Human Medicine and physicians from Spectrum Health have identified for the first time in a human patient a genetic disorder only previously described in animal models.
Preliminary results from a phase I clinical trial have demonstrated the safety and tolerability of a cell therapy involving the ex vivo expansion of T cells and their subsequent infusion into HIV-infected individuals previously ...
A series of illustrations and charts designed as decision aids for parents of children with minor head injuries helped them communicate with emergency medicine physicians and make informed decisions about their child's care, ...
A therapeutic vaccine can boost antibodies and T cells, helping them infiltrate tumors and fight off human papillomavirus (HPV)-related head and neck cancer. Researchers from the Abramson Cancer Center of the University of ...
A new study has shed light on the mechanisms underlying the progression of prion diseases and identified a potential target for treatment.
