Parkinson's disease and Amyotrophic Lateral Sclerosis are the newest frontiers for open science drug discovery, a global movement led by academic scientists in Toronto that puts knowledge sharing and medication affordability ...
Feb 15, 2019
2
3
High cholesterol has been found to be a possible risk factor for the development of motor neurone disease (MND), according to a large study of genetic data led in the UK by Queen Mary University of London, in collaboration ...
Feb 14, 2019
0
3
Researchers at the University of Sheffield have identified a new pathway that is disrupted in motor neurone disease (MND), a discovery which could pave the way for new treatments.
Feb 13, 2019
0
14
A team from Université Laval and the CERVO Brain Research Centre has demonstrated the efficacy in mice of a new therapy that addresses the main manifestation of amyotrophic lateral sclerosis (ALS). The researchers developed ...
Feb 06, 2019
0
1
Scientists from the University of Bath have shown that the zebrafish is a useful model to study a molecule called Rnasel-1, a counterpart to human Angiogenin, a molecule linked to the neurodegenerative disease ALS (Amyotrophic ...
Feb 06, 2019
0
12
Scientists from the University of Sheffield have identified new messenger molecules shuttled between cells which could help to protect the survival of neurones—potentially leading to new treatments for MND.
Feb 01, 2019
1
22
New research reveals RNAs, which are crucial for cells to produce proteins, are also involved in protein aggregation, where proteins do not fold properly and 'clump' together into aggregates. If cells cannot clear these away, ...
Feb 08, 2019
0
2
Research led by stem cell scientists at Harvard University points to a potential new biomarker and drug target for amyotrophic lateral sclerosis (ALS), a neurological disease that is extremely difficult to diagnose and treat. ...
Jan 15, 2019
0
231
Oral spray containing two compounds derived from the cannabis plant reduced spasticity compared with placebo in patients already taking anti-spasticity drugs.
Dec 14, 2018
0
12
Scientists from the University of Sheffield have successfully created zebrafish that carry the complex genetic change known to cause the most common genetic form of motor neurone disease (MND).
Nov 26, 2018
0
2
A small molecule, Sephin1, may be able to significantly delay harm to nerve cells caused by multiple sclerosis, a disabling immune-mediated disease that damages nerve fibers in the brain and spinal cord.
Jan 16, 2019
0
126
Both genes and the environment shape a person's risk of disease, but while genes are frequently cataloged, perturbed, activated, turned off and systematically tested in the lab, environmental exposures are often studied as ...
Jan 17, 2019
0
107
Neurology experts from around the world will convene November 27 in Auckland, New Zealand, for a conference on "brain health," examining what one calls "the greatest challenge of societies in the 21st century." Among the ...
Nov 26, 2018
0
4
Scientists have identified two distinct control mechanisms in the developmental transition of undifferentiated stem cells into healthy brain cells. This fundamental research using mice may inform regenerative medicine treatments ...
Dec 17, 2018
0
73
Nerve axons serve as the wiring of the nervous system, sending electrical signals that control movement and sense of touch. When axons are damaged, whether by injury or as a side effect of certain drugs, a program is triggered ...
Jan 17, 2019
0
76
Amyotrophic lateral sclerosis (ALS), also referred to as Lou Gehrig's disease in American English and Motor Neurone Disease in British English, is a form of Motor Neuron Disease caused by the degeneration of upper and lower neurons, located in the ventral horn of the spinal cord and the cortical neurons that provide their efferent input. The condition is often called Lou Gehrig's disease in North America, after the New York Yankees baseball player who was diagnosed with the disease in 1939. The disorder is characterized by rapidly progressive weakness, muscle atrophy and fasciculations, spasticity, dysarthria, dysphagia, and respiratory compromise. Sensory function generally is spared, as is autonomic and oculomotor activity. ALS is a progressive, fatal, neurodegenerative disease with most affected patients dying of respiratory compromise and pneumonia after 2 to 3 years; although some perish within a year from the onset of symptoms, and occasional individuals have a more indolent course and survive for many years.
This text uses material from Wikipedia licensed under CC BY-SA
