Amyotrophic lateral sclerosis (ALS) is a fast-progressing neurodegenerative disease with an average survival time of three years and no effective treatments. In ALS, motor neurons in the spinal cord, which are required for ...
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Motor neurons are nerve cells that control our muscles by sending signals from the brain and spinal cord out to the body. In diseases such as Amyotrophic Lateral Sclerosis (ALS), these cells are destroyed, leading to muscle ...
Jun 18, 2025
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Living close to cyanobacterial harmful algal blooms—which are present nationwide but are more common in coastal and Great Lakes states—heightens the rate of dying from amyotrophic lateral sclerosis, or ALS, a study suggests.
Jun 17, 2025
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A new study reveals striking international differences in how doctors approach the sensitive issue of tracheostomy invasive ventilation (TIV) for patients with amyotrophic lateral sclerosis (ALS). Cultural norms and health ...
Jun 12, 2025
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Researchers at the University of California, Davis, have developed an investigational brain-computer interface that holds promise for restoring the voices of people who have lost the ability to speak due to neurological conditions.
Jun 11, 2025
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Use of common psychiatric medications (anxiolytics, hypnotics and sedatives, and antidepressants) is linked to a higher risk of developing amyotrophic lateral sclerosis (ALS), and poorer outcomes after diagnosis with shorter ...
For patients with amyotrophic lateral sclerosis (ALS), rapid eye movement (REM) inhibition via receipt of antidepressant medication is associated with a trend toward survival benefit, according to a study presented at the ...
May 22, 2025
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During REM sleep, the body enters a state of paralysis. This can pose a danger for patients with weakened diaphragms due to neuromuscular diseases. Now new research published at the ATS 2025 International Conference has shown ...
May 21, 2025
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As researchers work to improve treatment of Alzheimer's disease, new research by UCLA Health identified a candidate drug that reduces levels of a toxic form of a protein in the brain caused by the disease and improved memory ...
May 21, 2025
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Unlike other pathologies, amyotrophic lateral sclerosis (ALS) cannot be reproduced accurately in animal models, complicating the development of effective drugs. Faced with this challenge, a group of researchers from IMDEA ...
May 13, 2025
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Amyotrophic lateral sclerosis (ALS), also referred to as Lou Gehrig's disease in American English and Motor Neurone Disease in British English, is a form of Motor Neuron Disease caused by the degeneration of upper and lower neurons, located in the ventral horn of the spinal cord and the cortical neurons that provide their efferent input. The condition is often called Lou Gehrig's disease in North America, after the New York Yankees baseball player who was diagnosed with the disease in 1939. The disorder is characterized by rapidly progressive weakness, muscle atrophy and fasciculations, spasticity, dysarthria, dysphagia, and respiratory compromise. Sensory function generally is spared, as is autonomic and oculomotor activity. ALS is a progressive, fatal, neurodegenerative disease with most affected patients dying of respiratory compromise and pneumonia after 2 to 3 years; although some perish within a year from the onset of symptoms, and occasional individuals have a more indolent course and survive for many years.
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