Amyotrophic lateral sclerosis (ALS) is a fatal progressive neurodegenerative disease that presents with various symptoms, such as muscle weakness, dysphagia, dysarthria, and respiratory failure, leading to death in 3–5 ...
Mar 18, 2022
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Immune cells could help predict the prognosis of patients with the rare neurological disease amyotrophic lateral sclerosis (ALS), says a study published today in eLife.
Mar 15, 2022
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A new paper in Annals of Neurology describes the approach, structure, and launch of the HEALEY ALS Platform Trial—the first platform trial for amyotrophic lateral sclerosis (ALS)—designed to accelerate the development ...
Feb 28, 2022
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A clinical trial conducted by Prof. Alexandra Durr's team (Sorbonne University.AP-HP) at the Paris Brain Institute and the Pitié-Salpêtrière Hospital AP-HP shows that despite the hopes raised in recent years, riluzole ...
Jan 19, 2022
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An international collaboration led by Flinders University has identified a potential biomarker for amyotrophic lateral sclerosis (ALS), also known as Motor Neuron Disease (MND), providing a way to test the effectiveness of ...
Jan 13, 2022
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Riluzole, a drug approved to treat amyotrophic lateral sclerosis (ALS), a disease affecting nerve cells controlling movement, could slow the gradual loss of a particular brain cell that occurs in Niemann-Pick disease type ...
Nov 19, 2021
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Amyotrophic lateral sclerosis (ALS), characterised by harm to brain neurons and to the spinal cord, also affects the tissue of the retina, according to a study headed up by Universidad Complutense de Madrid (UCM).
Nov 16, 2021
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A team led by investigators at Massachusetts General Hospital (MGH) has shown that people living with amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, who carry a mutation in the C9orf72 gene exhibit elevated ...
Nov 15, 2021
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Amyotrophic lateral sclerosis (ALS) is an intractable neurological disease. Aging is a risk factor for the accumulation of TDP-43 (transduction responsive region DNA-binding protein of 43kDa) in the motor cortex. TDP-43 is ...
Sep 29, 2021
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Researchers in Singapore have discovered that brain cells cannot maintain the cholesterol-rich myelin sheath that protects and insulates neurons in the absence of a protein called TDP-43. The study, which will be published ...
Aug 4, 2021
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