Immunology
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May 10, 2023
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Anaphylactic Shock
Neuroscience
Study identifies key role for nervous system in severe allergic shock
A key feature of the severe allergic reaction known as anaphylaxis is an abrupt drop in blood pressure and body temperature, causing people to faint and, if untreated, potentially die.
Mar 17, 2023
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Vaccination
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Vaccination
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Immunology
Researchers identify a new molecular mechanism related to severe anaphylaxis
Anaphylaxis is a systemic allergic reaction that can affect the skin, the gastrointestinal tract, the respiratory system and the cardiovascular system. The most severe form of anaphylaxis is anaphylactic shock, which features ...
Feb 9, 2021
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Diseases, Conditions, Syndromes
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Vaccination
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Immunology
New pill could prevent anaphylaxis in people with food, drug allergies
For someone with a food or drug allergy, the risk of life-threatening anaphylactic shock lurks around every corner. A new Northwestern Medicine study shows there might be a pill that can be taken proactively to prevent mild ...
Jun 3, 2020
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82
Medical research
Anaphylactic shock: Anti-drug IgG antibodies and neutrophils play an unexpected role
Anaphylactic shock, an exacerbated allergic reaction that can prove fatal, is sometimes caused by the use of drugs during surgery. In most of these extreme reactions, evidence can be provided that patients have anti-drug ...
Jul 10, 2019
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65
Immunology
Using mice, researchers identify how allergic shock occurs so quickly
When someone has a severe allergy, the life-threatening effects of an exposure are nearly instantaneous—skin rash, fainting, labored breathing, weak pulse, racing heart.
Nov 8, 2018
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85
Anaphylaxis is defined as "a serious allergic reaction that is rapid in onset and may cause death". It typically results in a number of symptoms including an itchy rash, throat swelling, and low blood pressure. Common causes include insect bites, foods, and medications.
On a pathophysiologic level, anaphylaxis is due to the release of mediators from certain types of white blood cells triggered either by immunologic or non-immunologic mechanisms. It is diagnosed based on the presenting symptoms and signs. The primary treatment is injection of epinephrine, with other measures being complementary.
Worldwide 0.05–2% of people are estimated to have anaphylaxis at some point in their life and rates appear to be increasing. The term comes from the Greek words ἀνά ana, against, and φύλαξις phylaxis, protection.
This text uses material from Wikipedia licensed under CC BY-SA
