Asthma

Immune signature predicts asthma susceptibility

Asthma is a chronic inflammatory disease driven by the interplay of genetics, environmental factors and a diverse cast of immune cells. In their latest study, researchers at La Jolla Institute for Allergy and Immunology (LJI) ...

Feb 16, 2018
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New molecular target could help ease asthma

Researchers at UC Davis Health and Albany Medical College have shown that the protein vascular endothelial growth factor A—or VEGFA—plays a major role in the inflammation and airway obstruction associated with asthma.

Mar 07, 2018
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How allergens trigger asthma attacks

A team of Inserm and CNRS researchers from the Institute of Pharmacology and Structural Biology have identified a protein that acts like a sensor detecting allergens in the respiratory tract that are responsible for asthma ...

Mar 19, 2018
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Asthma drug potential treatment for aortic aneurysm

Aortic aneurysm – the dilation of the aorta – is a serious condition that lacks effective drug treatment. Researchers at Karolinska Institutet report in the journal PNAS, however, that a common asthma drug can retard ...

Feb 06, 2018
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Asthma (from the Greek άσθμα, ásthma, "panting") is the common chronic inflammatory disease of the airways characterized by variable and recurring symptoms, reversible airflow obstruction, and bronchospasm. Symptoms include wheezing, coughing, chest tightness, and shortness of breath. Asthma is clinically classified according to the frequency of symptoms, forced expiratory volume in 1 second (FEV1), and peak expiratory flow rate. Asthma may also be classified as atopic (extrinsic) or non-atopic (intrinsic).

It is thought to be caused by a combination of genetic and environmental factors. Treatment of acute symptoms is usually with an inhaled short-acting beta-2 agonist (such as salbutamol). Symptoms can be prevented by avoiding triggers, such as allergens and irritants, and by inhaling corticosteroids. Leukotriene antagonists are less effective than corticosteroids and thus less preferred.

Its diagnosis is usually made based on the pattern of symptoms and/or response to therapy over time. The prevalence of asthma has increased significantly since the 1970s. As of 2010, 300 million people were affected worldwide. In 2009 asthma caused 250,000 deaths globally. Despite this, with proper control of asthma with step down therapy, prognosis is generally good.

This text uses material from Wikipedia licensed under CC BY-SA

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