Genetics

Chromosome 'bumper repair' gene predicts cancer patient outcomes

Like a car's front and back bumpers, your cell's chromosomes are capped by "telomeres" that protect this genetic material against deterioration. Still, after enough replications, a chromosome's telomeres break down and once ...

Oncology & Cancer

Researchers discover one of the genetic pieces of bladder cancer

Notch genes are a double-edged sword: in some cancers they have a harmful effect because they promote tumour growth, whilst in others they act as tumour suppressors. The reason is still unclear, making it impossible to predict ...

Oncology & Cancer

Practice makes perfect in cancer surgery

In a new, in-depth research project, Queen's professors Rob Siemens (Urology) and Christopher Booth (Cancer Care and Epidemiology) investigated what affect higher volume hospitals and surgeons had on the outcomes of patients ...

Oncology & Cancer

How 'trained immunity' mediates BCG therapy of bladder cancer

Bacillus Calmette-Guerin (BCG) is a vaccine widely used in low and middle-income countries to protect against childhood tuberculosis. Besides its specific anti-tuberculosis effects, BCG can also function as a general immune-booster, ...

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