A first-in-class peptide-based PET tracer, 18F-AlF-NOTA-PCP2, can effectively measure PD-L1 expression in patients with head and neck cancers, outperforming the conventional tracer 18F-FDG. 18F-AlF-NOTA-PCP2 uptake strongly ...
17 hours ago
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Hepatocellular carcinoma (HCC), the most common type of liver cancer and the third-leading cause of cancer-related deaths worldwide, is extremely challenging to treat. However, the future of HCC patient care looks brighter ...
18 hours ago
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A research team led by Prof. Li Hai from the Hefei Institutes of Physical Science of the Chinese Academy of Sciences has become the first to systematically explore how large language models (LLMs) can assist in predicting ...
Jun 18, 2025
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A research team from the School of Clinical Medicine of the LKS Faculty of Medicine of the University of Hong Kong (HKUMed) has pioneered the use of a 'dual immunotherapy' combination—nivolumab and ipilimumab (NIVO+IPI)—in ...
Jun 16, 2025
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Pembrolizumab, an immune checkpoint inhibitor, has been approved by the U.S. Food and Drug Administration (FDA) for the treatment of patients with resectable locally advanced head and neck squamous cell carcinoma whose tumors ...
Jun 14, 2025
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Scientists have discovered tumors can tap a nontraditional pathway to acquire lipoproteins—molecules that transport fat in blood—which enriches cancer cells with an antioxidant shield to survive stress, according to new ...
Jun 12, 2025
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Hepatitis C virus (HCV) infection is highly associated with the development of metabolic dysfunction-associated steatotic liver disease (MASLD), with a diagnosis requiring the presence of steatotic liver disease (SLD) along ...
Jun 9, 2025
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JoEllen Zembruski-Ruple, while in the care of New York City's renowned Memorial Sloan Kettering Cancer Center, swallowed the first three chemotherapy pills to treat her squamous cell carcinoma on Jan. 29, her family members ...
Jun 9, 2025
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A genetic mutation that fuses two genes drives several different cancer types by forming networks of protein interactions that alter gene expression in cells, a study by UT Southwestern Medical Center researchers suggests. ...
Jun 5, 2025
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A drug already approved by the FDA to treat menopause symptoms may also help prevent invasive breast cancer, according to new findings from a multi-center phase 2 clinical trial led by Northwestern Medicine.
May 29, 2025
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Carcinoma (Gk. karkinos, or "crab", and -oma, "growth") is the medical term for the most common type of cancer occurring in humans. Put simply, a carcinoma is a cancer that begins in a tissue that lines the inner or outer surfaces of the body, and that generally arises from cells originating in the endodermal or ectodermal germ layer during embryogenesis. More specifically, a carcinoma is tumor tissue derived from putative epithelial cells whose genome has become altered or damaged to such an extent that the cells become transformed, and begin to exhibit abnormal malignant properties.
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