Chronic Inflammatory Disease

Endogenous peptide lowers cholesterol

Cells of the innate immune system that play an important role in development of atherosclerosis contain a protein that reduces levels of cholesterol in mice – and thus helps to inhibit or mitigate the disease.

11 hours ago
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Can coffee perk up heart health, too?

The caffeine in your morning cup of joe may do more than jolt you awake—it may also help dampen the type of inflammation that's linked to heart disease risk factors, a new study suggests.

Jan 16, 2017
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Metabolic sensor causes granulomas to form

Granulomas are tissue nodules of immune cells that occur in diseases such as tuberculosis and sarcoidosis and can damage many organs. For the first time, a team of researchers at the Center for Pathobiochemistry and Genetics ...

Jan 16, 2017
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Every meal triggers inflammation

When we eat, we do not just take in nutrients – we also consume a significant quantity of bacteria. The body is faced with the challenge of simultaneously distributing the ingested glucose and fighting these bacteria. This ...

Jan 17, 2017
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As cells age, the fat content within them shifts

As cells age and stop dividing, their fat content changes, along with the way they produce and break down fat and other molecules classified as lipids, according to a new University at Buffalo study.