Cancer stem cells are like zombies—even after a tumor is destroyed, they can keep coming back. These cells have an unlimited capacity to regenerate themselves, making more cancer stem cells and more tumors. Researchers ...
Jun 9, 2016
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Despite treatment with imatinib, a successful drug that targets chronic myeloid leukemia (CML), a deadly type of cancer, some patients may continue to be at risk for relapse because a tiny pool of stem cells is resistant ...
Dec 9, 2012
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(AP) -- In a case that could affect India's role as drug provider to the developing world, the Supreme Court began hearing arguments Tuesday over whether the government had the right to deny a patent to Swiss drugmaker Novartis ...
Sep 6, 2011
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An international team, headed by researchers at the University of California, San Diego School of Medicine, has identified a key enzyme in the reprogramming process that promotes malignant stem cell cloning and the growth ...
Dec 24, 2012
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Researchers at the University of California, San Diego School of Medicine have discovered that hard-to-reach, drug-resistant leukemia stem cells (LSCs) that overexpress multiple pro-survival protein forms are sensitive – ...
Jan 17, 2013
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After decades of studying the pathological process that wipes out large volumes of memory, scientists at The Feinstein Institute for Medical Research discovered a molecule called c-Abl that has a known role in leukemia also ...
May 24, 2011
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A new study by researchers at University of California, San Diego School of Medicine reveals a protein's critical - and previously unknown—role in the development and progression of acute myeloid leukemia (AML), a fast-growing ...
Jul 23, 2015
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This is the story of Abl and Src—two nearly identical protein kinases whose evolution may hold the key to unlocking new, highly specific cancer drugs.
Feb 19, 2015
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Researchers at Huntsman Cancer Institute (HCI) at the University of Utah have identified and characterized mutated forms of the gene that encodes BCR-ABL, the unregulated enzyme driving the blood cancer chronic myeloid leukemia ...
Aug 20, 2014
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Chronic myeloid leukemia (CML) is a type of blood cancer that arises from malignant changes in blood-forming cells of the bone marrow. It mainly occurs in older individuals and represents about 20% of all adult leukemia cases.
May 16, 2023
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