Immunology

Immune responses in chronic inflammatory bowel diseases

Chronic inflammatory bowel diseases (IBDs) like Crohn's disease and ulcerative colitis are characterized by inflammation of the gastrointestinal tract which flares up in phases and which is accompanied by abdominal pain, ...

Immunology

Deciphering gut microbiome 'chatter' to combat IBD

Around 500,000 people in the UK live with Inflammatory Bowel Disease (IBD), a life-long, chronic condition characterized by sporadic bouts of gut inflammation causing debilitating symptoms. Crohn's Disease and Ulcerative ...

Oncology & Cancer

Pediatric-onset inflammatory bowel disease may up cancer risk

Patients with pediatric-onset inflammatory bowel disease (IBD) may have an increased risk for developing cancer, particularly gastrointestinal cancers, according to a meta-analysis published online March 1 in JAMA Network ...

Gastroenterology

CRP can help assess severity of acute ulcerative colitis

(HealthDay)—A C-reactive protein (CRP) cutoff is a sensitive and practical alternative to erythrocyte sedimentation rate (ESR) as a criterion to help determine ulcerative colitis (UC) activity, according to a study published ...

Medical research

Infusion of 3D cellular structures might repair damaged intestine

Ulcerative colitis is an inflammatory bowel disease (IBD) that causes inflammation and ulcers (sores) in the digestive tract. Ulcerative colitis affects the innermost lining of the colon and rectum. It can be a debilitating ...

Immunology

Newly identified protein may help diagnose ulcerative colitis

An international research collaboration has discovered a potential new diagnostic marker for ulcerative colitis in a trans-ethnic analysis of Japanese and white patients. The finding could lead to the development of non-invasive, ...

Medical research

Stool samples reveal microbial enzyme driving bowel disease

Ulcerative colitis, a subtype of inflammatory bowel disease, is a chronic ailment of the colon affecting nearly one million individuals in the United States. It is thought to be linked to disruptions in the gut microbiome—the ...

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