Alzheimer's disease & dementia

Brain changes linked with Alzheimer's years before symptoms appear

In a records review of 290 people at risk for Alzheimer's disease, scientists at Johns Hopkins say they have identified an average level of biological and anatomical brain changes linked to Alzheimer's disease that occur ...

Alzheimer's disease & dementia

Early-stage detection of Alzheimer's in the blood

Using current techniques, Alzheimer's disease, the most frequent cause of dementia, can only be detected once characteristic plaques have formed in the brain. At this point, therapy is no longer possible. However, the first ...

Neuroscience

Clowning around is good for brain health

Trinity College and the Global Brain Health Institute (GBHI) are broadening the discussion on the importance of art for brain health which gives space for perspectives that may help change the narrative on how we view older ...

Neuroscience

rTMS improves memory in younger and older adults

Magnetic stimulation of the brain improves working memory, offering a new potential avenue of therapy for individuals living with Alzheimer's disease and other forms of dementia, according to new research from the Duke University ...

Medications

Potential drug targets for ALS and FTD identified in two studies

A pair of collaborative studies led by Fen-Biao Gao, Ph.D., have identified two potential drug targets for the diseases amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). The studies, which appear in Nature ...

Alzheimer's disease & dementia

Artificial intelligence tool vastly scales up Alzheimer's research

Researchers at UC Davis and UC San Francisco have found a way to teach a computer to precisely detect one of the hallmarks of Alzheimer's disease in human brain tissue, delivering a proof of concept for a machine-learning ...

Alzheimer's disease & dementia

A comprehensive map of how Alzheimer's affects the brain

MIT researchers have performed the first comprehensive analysis of the genes that are expressed in individual brain cells of patients with Alzheimer's disease. The results allowed the team to identify distinctive cellular ...

Diseases, Conditions, Syndromes

Antibiotics: Why asking doctors' to prescribe less is futile

An 85-year-old woman with dementia is admitted to hospital with worsening confusion, new urinary incontinence and constipation. These symptoms suggest a urinary tract infection, but the doctor treating her has a dilemma because ...

Medical research

Preventing relapse in recovery from cocaine use disorder

A study conducted at the University of São Paulo (USP) in Brazil and described in an article published in the journal Drug and Alcohol Dependence may help healthcare workers identify patients who risk relapse after undergoing ...

Alzheimer's disease & dementia

New Alzheimer therapy passes another important test

The Alzheimer drug candidate PRI-002 developed at Forschungszentrum Jülich has successfully completed Phase I of clinical research involving healthy volunteers. When administered daily over a period of four weeks, the active ...

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