Medications
Deprescribing efforts failing dementia patients, study finds
Researchers led by the Beth Israel Deaconess Medical Center, Boston, have examined how a dementia diagnosis impacts medication use patterns in older adults.
Dementia
Genetics
Study unveils new RNA dysregulation process that contributes to neurodegeneration
Recent neuroscience studies have consistently outlined the role of the C9ORF72 gene in the development of some neurodegenerative diseases. These studies found that mutations of this gene increase the risk of developing amyotrophic ...
Psychology & Psychiatry
Alzheimer's risk: Many say they want answers, but fewer choose to know the truth
As researchers make progress in understanding how Alzheimer's disease develops, there are growing opportunities for healthy research participants to learn their risk of developing Alzheimer's disease dementia in the future. ...
May 6, 2025
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Alzheimer's disease & dementia
Speech and hearing tests allow early detection of rare type of dementia that affects language
Difficulty finding words or the habit of substituting them with others that are similar semantically—such as knife and cutter—or phonologically—such as knife and wife—are usually the first symptoms of a type of dementia ...
May 1, 2025
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4
Neuroscience
Live human brain tissue reveals how Alzheimer's-linked protein damages connections
Scientists using living human brain tissue have shown for the first time how a toxic form of a protein linked to Alzheimer's can stick to and damage the connections between brain cells.
Apr 30, 2025
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Genetics
A protein link between brain diseases and leaky blood vessels
Reduced levels of a critical protein are linked to devastating brain diseases like Alzheimer's, frontotemporal dementia, and amyotrophic lateral sclerosis (ALS). Surprisingly, the protein shortage primarily affects the brain's ...
Apr 30, 2025
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Neuroscience
How resilient nerve cells fight back against dementia
A UCL research team has found clues as to why some nerve cells die in dementia and not others, through a new study in fruit flies. The study, published in Cell Reports, is helping to answer one of the biggest questions in ...
Apr 29, 2025
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Cardiology
Getting treatment for high blood pressure may reduce chances of developing dementia
Reducing high blood pressure substantially lowers the risk of dementia and cognitive impairment without dementia, according to the results of a phase 3 clinical trial involving almost 34,000 patients, published in Nature ...
Apr 21, 2025
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Alzheimer's disease & dementia
Hospital visits for cannabis use linked to higher dementia risk
Individuals with an emergency department (ED) visit or hospitalization due to cannabis were at 23% and 72% greater risk of a new dementia diagnosis within five years compared to individuals with an ED visit or hospitalization ...
Apr 14, 2025
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Neuroscience
Discovery of α-synuclein's 'fuzzy coat' mechanism offers new insights into Parkinson's
Parkinson's disease (PD) and Lewy body dementia (LBD) are incurable and progressive neurodegenerative disorders, with some overlapping symptoms. An estimated 10 million people worldwide live with PD, while the figure for ...
Apr 11, 2025
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