Genetics

Innovative approach maps gene activity in the living human brain

A new method to profile gene activity in the living human brain has been developed by researchers at FutureNeuro, the Research Ireland Center for Translational Brain Science and RCSI University of Medicine and Health Sciences, ...

Diseases, Conditions, Syndromes

Finland introduces a new care pathway for epilepsy

The Finnish epilepsy care pathway has been published in Epilepsia Open. This Finnish model for epilepsy care provides a streamlined, multidisciplinary approach to the diagnosis and treatment of epilepsy, and combines modern ...

Neuroscience

Neuroscientists look for clues to stop seizures

Using deep brain stimulation techniques, neuroscientists at Mayo Clinic are looking for early signals in the brain to help stop seizures. In their biomarker discovery initiative, a team of researchers is assessing how different ...

Neuroscience

Understanding epilepsy: Insights from a child neurologist

Epilepsy is a common but complex neurological disorder that impacts millions of people worldwide. It occurs when groups of neurons in the brain send abnormal signals, leading to seizures. These seizures, which come in various ...

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Epilepsy (from the Ancient Greek ἐπιληψία (epilēpsía) — "seizure") is a common and diverse set of chronic neurological disorders characterized by seizures. Some definitions of epilepsy require that seizures be recurrent and unprovoked, but others require only a single seizure combined with brain alterations which increase the chance of future seizures.

Epileptic seizures result from abnormal, excessive or hypersynchronous neuronal activity in the brain. About 50 million people worldwide have epilepsy, and nearly 90% of epilepsy occurs in developing countries. Epilepsy becomes more common as people age. Onset of new cases occur most frequently in infants and the elderly. As a consequence of brain surgery, epileptic seizures may occur in recovering patients.

Epilepsy is usually controlled, but not cured, with medication. However, over 30% of people with epilepsy do not have seizure control even with the best available medications. Surgery may be considered in difficult cases. Not all epilepsy syndromes are lifelong – some forms are confined to particular stages of childhood. Epilepsy should not be understood as a single disorder, but rather as syndromic with vastly divergent symptoms, all involving episodic abnormal electrical activity in the brain and numerous seizures.

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