Genetics

Custom alterations: Mending genes for long-lasting effects

Gene-editing therapies—techniques that modify DNA to treat or prevent disease—have the potential to transform the field of drug development. By making precise edits to the genome, problematic genes could be modified or ...

Diseases, Conditions, Syndromes

Understanding liver fibrosis: Insights from Alagille syndrome

What influences the extent of scar tissue, or fibrosis, that develops in the liver when people suffer from liver disease? While a small amount of fibrosis is a normal part of the healing process, excessive fibrosis can occur, ...

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