Neuroscience
Huntington's research results in treatment advance
Treatment of Huntington's disease may become more targeted and individualised as a result of research at the University of Auckland's Centre for Brain Research.
Jun 20, 2014
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Huntington Disease
Neuroscience
Healthy tissue grafted to the brains of Huntington's patients also develops the disease
A recent study published in Annals of Neurology reports that healthy human tissue grafted to the brains of patients with Huntington's disease in the hopes of treating the neurological disorder also developed signs of the ...
Jun 5, 2014
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Neuroscience
Promising approach to slow brain degeneration in a model of Huntington's disease
Research presented by Dr. Lynn Raymond, from the University of British Columbia, shows that blocking a specific class of glutamate receptors, called extrasynaptic NMDA receptors, can improve motor learning and coordination, ...
May 25, 2014
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Genetics
Novel RNAi therapy silences mutated Huntington's disease gene and reduces symptoms
A targeted gene silencing strategy blocks production of the dysfunctional huntingtin (Htt) protein, the cause of Huntington's disease, a fatal, inherited neurodegenerative disorder. The effectiveness of this RNA interference ...
May 21, 2014
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Neuroscience
Scientists hunt down origin of Huntington's disease in the brain
The gene mutation that causes Huntington's disease appears in every cell in the body, yet kills only two types of brain cells. Why? UCLA scientists used a unique approach to switch the gene off in individual brain regions ...
Apr 28, 2014
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Medical research
Protein clusters implicated in neurodegenerative diseases actually serve to protect brain cells
People diagnosed with Huntington's disease, most in their mid-thirties and forties, face a devastating prognosis: complete mental, physical, and behavioral decline within two decades. "Mutant" protein clusters, long blamed ...
Apr 23, 2014
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Medical research
Unlocking a mystery of Huntington's disease in space
(Medical Xpress)—An experiment just launched into orbit by a team of Caltech researchers could be an important step toward understanding a devastating neurodegenerative disease.
Apr 21, 2014
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Neuroscience
Huntington's disease: Study discovers potassium boost improves walking in mouse model
Tweaking a specific cell type's ability to absorb potassium in the brain improved walking and prolonged survival in a mouse model of Huntington's disease, reports a UCLA study published March 30 in the online edition of Nature ...
Mar 30, 2014
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Neuroscience
Brain degeneration in Huntington's disease caused by amino acid deficiency
Working with genetically engineered mice, Johns Hopkins neuroscientists report they have identified what they believe is the cause of the vast disintegration of a part of the brain called the corpus striatum in rodents and ...
Mar 26, 2014
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Parkinson's & Movement disorders
Research reveals new therapeutic targets for Huntington's and Parkinson's disease
(Medical Xpress)—Research from Western University has revealed a possible new target for treating movement disorders such as Huntington's disease (HD) and Parkinson's disease. Stephen Ferguson, PhD, a scientist at Western's ...
Mar 14, 2014
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