Huntington's disease is a genetically-based neurodegenerative disorder that causes motor, cognitive and psychiatric disorders in the affected individuals. Understanding the alterations in the neural circuits in this disorder ...
Jun 7, 2023
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The drug valbenazine statistically improves chorea, a movement disorder commonly associated with Huntington's disease, when compared to a placebo, according to a recent international study led by UTHealth Houston researcher ...
May 19, 2023
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Cambridge scientists have shown how the brain's ability to clear out toxic proteins is impaired in Huntington's disease and other forms of dementia—and how, in a study in mice, a repurposed HIV drug was able to restore ...
Apr 26, 2023
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A team with the participation of researchers from the Institute for Advanced Chemistry of Catalonia (IQAC) of the Spanish National Research Council (CSIC) has revealed the structure of the protein responsible for Huntington's ...
Apr 20, 2023
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Investigators led by D. James Surmeier, Ph.D., the Nathan Smith Davis Professor and chair of Neuroscience, have uncovered previously unknown neuronal circuits that contribute to brain dysfunction in Huntington's disease.
Apr 17, 2023
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Neurodegenerative disorders such as Alzheimer, Parkinson and Huntington disease each cause their own distinct set of symptoms, yet they share a common feature: abnormal protein aggregation. It's been unknown if overlapping ...
Mar 23, 2023
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In patients with Huntington's disease, neurons in a part of the brain called the striatum are among the hardest-hit. Degeneration of these neurons contributes to patients' loss of motor control, which is one of the major ...
Jan 20, 2023
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A perplexing range of neurodegenerative diseases are known to attack distinct regions of the brain, causing severe cognitive and motor deficit. The combined impact of these (generally fatal) diseases has inflicted a devastating ...
Dec 21, 2022
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Researchers at the University of Miami Miller School of Medicine, McGill University and other institutions have found that a well-concealed genetic variation in the gene FGF14, called a DNA tandem repeat expansion, causes ...
Dec 14, 2022
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Huntington's disease (HD) is a neurological disorder that causes progressive loss of movement, coordination and cognitive function. It is caused by a mutation in a single gene called huntingtin (HTT). More than 200,000 people ...
Dec 12, 2022
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