Telomeres are to chromosomes what aglets are to shoelaces—protective caps that stop the tightly wound strings from unraveling. Every time a cell divides, its telomeres are trimmed, eventually becoming so short that the ...
Feb 11, 2016
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Living longer usually means a longer dotage, but wouldn't it be enticing to extend young adulthood instead? It's such an appealing prospect that scientists who are announcing success with roundworms are keen to be clear they ...
Dec 2, 2015
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Children who suffer from Hutchinson-Gilford Progeria syndrome age prematurely due to a defective protein in their cells. Scientists at Technische Universität München have now identified another important pathological factor: ...
Dec 17, 2014
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Researchers from Salk Institute for Biological Studies, BGI, and other institutes for the first time evaluated the safety and reliability of the existing targeted gene correction technologies, and successfully developed a ...
Jul 11, 2014
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Scientists at the University of Cambridge have identified a key chemical that can repair the damage to cells which causes a rare but devastating disease involving accelerated ageing. As well as offering a promising new way ...
May 1, 2014
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Pharmaceuticals that inhibit a specific enzyme may be useful in treating progeria, or accelerated aging in children. A new study performed at the Sahlgrenska Academy indicates that the development of progeria in mice was ...
May 16, 2013
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A study conducted by researchers at Boston University School of Medicine (BUSM) provides new evidence that longwave ultraviolet light (UVA) induces a protein that could result in premature skin aging. The findings demonstrate ...
Apr 25, 2013
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Misshapen cell nuclei are frequently observed in the cells of people with cancer and other diseases, but what causes the abnormality—and why it is associated with certain disorders—has remained unclear.
Feb 19, 2013
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Results of the first-ever clinical drug trial for children with Progeria, a rare, fatal "rapid-aging" disease, demonstrate the efficacy of a farnesyltransferase inhibitor (FTI), a drug originally developed to treat cancer. ...
Sep 24, 2012
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Researchers have identified a potential drug therapy for a premature ageing disease that affects children causing them to age up to eight times as fast as the usual rate.
Nov 2, 2011
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