Inflammatory disorders

Dual functions of the Interleukin-1 Receptor-Like 2 cytokine

The Interleukin-1 Receptor-Like 2 (IL-1RL2) cytokine can promote inflammatory diseases and have a role in controlling infection. The receptor can recognize multiple agonists and has been implicated in the development of inflammatory ...

Pediatrics

New therapeutic options for childhood inflammatory bowel disease

Inflammatory bowel disease (IBD) affects approximately 40,000 patients in Ireland, with 25% of these cases first arising during childhood. Globally, the prevalence for IBD is 396 cases per 100,000 persons annually. Symptoms ...

Medical research

Infusion of 3D cellular structures might repair damaged intestine

Ulcerative colitis is an inflammatory bowel disease (IBD) that causes inflammation and ulcers (sores) in the digestive tract. Ulcerative colitis affects the innermost lining of the colon and rectum. It can be a debilitating ...

Immunology

Newly identified protein may help diagnose ulcerative colitis

An international research collaboration has discovered a potential new diagnostic marker for ulcerative colitis in a trans-ethnic analysis of Japanese and white patients. The finding could lead to the development of non-invasive, ...

Gastroenterology

Can we harness intestinal cells to treat endocrine disorders?

Enteroendocrine cells punch above their weight. Constituting just about 1 percent of intestinal cells, they produce, as a group, around 15 different hormones. These not only regulate intestinal function and digestion, but ...

Inflammatory disorders

Scientists reveal mechanism for colon pain and inflammation

Researchers at the NYU Pain Research Center have identified a mechanism that underlies inflammation and pain in the colon, and demonstrated that blocking a key receptor from entering colon cells can inhibit inflammation and ...

Gastroenterology

Certain dietary patterns may raise risk for developing IBD

(HealthDay)—Dietary patterns are associated with the risk for developing inflammatory bowel disease (IBD), with an increased risk for Crohn disease (CD) seen in association with a Western dietary pattern and an increased ...

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