Advances in cardiac imaging techniques and risk categorization have led to improvements in diagnosis, initial treatment and long-term management of patients with Kawasaki disease, according to a new scientific statement published ...
Nov 13, 2024
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RNA performs a number of biological duties, from delivering genetic information to manufacturing proteins. But RNA is also expelled from cells via cell death or active release, and can then find its way into blood plasma.
Sep 9, 2024
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A study led by ISGlobal shows that the incidence of Kawasaki disease in Japan increases when fine metal-laden aerosols are detected in the atmosphere. These aerosols come from the area known as the "breadbasket of China," ...
Jun 21, 2023
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A new tool under development by University at Buffalo researchers could one day help clinicians better predict resistance to immunoglobulin therapy among children with Kawasaki disease in the United States.
Dec 2, 2022
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For children with rare heart conditions such as Kawasaki disease, heart failure or congenital heart defects that increase the risk of blood clots, a daily anti-clotting pill may safely allow them to avoid the frequent injections, ...
Oct 31, 2022
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One of the rare complications of COVID in children is an inflammatory illness called paediatric inflammatory multisystem syndrome (PIMS-TS) that occurs in the weeks following the time of infection with SARS-CoV-2 (the virus ...
Jun 7, 2022
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The emergence of COVID-19 had doctors racing to define and treat the new disease, but they soon discovered it was not the only novel illness caused by SARS-CoV-2. A subset of children infected by the virus also experienced ...
May 16, 2022
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The American College of Rheumatology (ACR), in partnership with the Vasculitis Foundation (VF), released a new guideline for the management of Kawasaki disease that addresses diagnostic issues relating to Kawasaki disease, ...
Mar 8, 2022
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(HealthDay)—Respiratory infections in children are associated with Kawasaki disease (KD) at one to three months before KD outbreaks, according to a study published online Feb. 7 in JAMA Network Open.
Feb 7, 2022
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Intravenous immune globulin (IVIG)—a common treatment for multisystem inflammatory syndrome in children (MIS-C)—likely works by depleting immune cells called neutrophils, according to a recent study funded by the National ...
Oct 15, 2021
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Kawasaki disease (KD), also known as Kawasaki syndrome, lymph node syndrome and mucocutaneous lymph node syndrome, is an autoimmune disease in which the medium-sized blood vessels throughout the body become inflamed. It is largely seen in children under five years of age. It affects many organ systems, mainly those including the blood vessels, skin, mucous membranes and lymph nodes; however, its rare but most serious effect is on the heart where it can cause fatal coronary artery aneurysms in untreated children. Without treatment, mortality may approach 1%, usually within six weeks of onset. With treatment, the mortality rate is less than 0.01% in the U.S. There is often a pre-existing viral infection that may play a role in its pathogenesis. The conjunctivae and oral mucosa, along with the epidermis (skin), become erythematous (red and inflamed). Edema is often seen in the hands and feet and one or both of the cervical lymph nodes are often enlarged. Also, a remittent fever, often 40°C (104°F) or higher, is characteristic of the acute phase of the disease. In untreated children, the febrile period lasts on average approximately 10 days, but may range from five to 25 days. The disorder was first described in 1967 by Tomisaku Kawasaki in Japan.
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