Overweight & Obesity

J-shaped association seen for BMI, Hodgkin lymphoma

(HealthDay)—There is a strong positive association between body mass index (BMI) and incident Hodgkin lymphoma (HL), with the positive association seen at BMIs greater than 24.2 kg/m², according to a study recently published ...

Medical research

Advance in CAR T-cell therapy eliminates severe side effects

An advance in the breakthrough cancer treatment known as CAR T-cell therapy appears to eliminate its severe side effects, making the treatment safer and potentially available in outpatient settings, a new USC study shows.

Cancer

Q&A: PET scans important in assessing some forms of lymphoma

Dear Mayo Clinic: My father just started chemotherapy for lymphoma, and he is scheduled for a positron emission tomography or PET scan after his first three treatments. How do doctors decide when to perform a PET scan, and ...

Cancer

Colorectal neoplasia risk up for Hodgkin Lymphoma survivors

(HealthDay)—Hodgkin lymphoma (HL) survivors have an increased risk for advanced colorectal neoplasia, including advanced adenomas, advanced serrated lesions, and serrated polyposis syndrome, according to a study published ...

Surgery

France to ban popular breast implants over cancer risk: media

France is to ban a popular type of breast implant which has been linked to a rare form of cancer, Le Monde newspaper and French public radio reported Wednesday, citing a letter from health authorities to implant manufacturers.

Diseases, Conditions, Syndromes

Researchers make progress toward Epstein-Barr virus vaccine

A research team led by scientists from NIH's National Institute of Allergy and Infectious Diseases (NIAID) has determined how several antibodies induced by Epstein-Barr virus (EBV), a herpesvirus that causes infectious mononucleosis ...

page 1 from 23

Lymphoma is a cancer of the lymphocytes, a type of cell that forms part of the immune system. Typically, lymphomas present as a solid tumor of lymphoid cells. Treatment might involve chemotherapy and in some cases radiotherapy and/or bone marrow transplantation, and can be curable depending on the histology, type, and stage of the disease. These malignant cells often originate in lymph nodes, presenting as an enlargement of the node (a tumor). It can also affect other organs in which case it is referred to as extranodal lymphoma. Extranodal sites include the skin, brain, bowels and bone. Lymphomas are closely related to lymphoid leukemias, which also originate in lymphocytes but typically involve only circulating blood and the bone marrow (where blood cells are generated in a process termed haematopoesis) and do not usually form static tumors. There are many types of lymphomas, and in turn, lymphomas are a part of the broad group of diseases called hematological neoplasms.

Thomas Hodgkin published the first description of lymphoma in 1832, specifically of the form named after him, Hodgkin's lymphoma. Since then, many other forms of lymphoma have been described, grouped under several proposed classifications. The 1982 Working formulation classification became very popular. It introduced the category non-Hodgkin lymphoma (NHL), divided into 16 different diseases. However, because these different lymphomas have little in common with each other, the NHL label is of limited usefulness for doctors or patients and is slowly being abandoned. The latest classification by the WHO (2008) lists 70 different forms of lymphoma divided in four broad groups.

Although older classifications referred to histiocytic lymphomas, these are recognized in newer classifications as of B, T or NK cell lineage. True histiocytic malignancies are rare and are classified as sarcomas.

This text uses material from Wikipedia licensed under CC BY-SA