Oncology & Cancer
An aspirin a day keeps the bowel doctor away
A regular dose of aspirin to reduce the risk of inherited bowel cancer lasts at least 10 years after stopping treatment, research has revealed.
Jun 12, 2020
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Lynch Syndrome
Oncology & Cancer
Testing people with bowel cancer for genetic syndrome could save lives and money
Lynch syndrome, a mutation of four genes involved in DNA repair, is associated with increased risk of developing a range of cancers, particularly colorectal cancer (CRC).
Oct 29, 2019
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2
Oncology & Cancer
Cancer preventive vaccine showed promising results in preclinical model of Lynch syndrome
Vaccination with as few as four tumor antigens generated antigen-specific responses, reduced intestinal tumors, and improved survival in a mouse model of Lynch syndrome, suggesting that it may be possible to develop a cancer ...
Apr 1, 2019
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161
Oncology & Cancer
Single agent treats two cancers with same genetic cause
(HealthDay)—A single checkpoint inhibitor can be used to successfully treat two simultaneous types of primary cancer in a patient with Lynch syndrome, according to a research letter published online Sept. 25 in the Annals ...
Sep 27, 2018
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1
Oncology & Cancer
Lynch syndrome found to be associated with more types of cancers
A team of researchers at Memorial Sloan Kettering Cancer Center has found Lynch syndrome to be associated with more types of cancer than previously thought. The group gave a presentation at this year's American Society of ...
Oncology & Cancer
Mesalazine attenuates tumour formation by 50% in hereditary bowel cancer cases
Around 5,000 Austrians a year develop a colorectal carcinoma, that is to say cancer of the colon or rectum. Around 5% of these are genetically predisposed and develop Lynch syndrome, the commonest genetic form of bowel cancer, ...
May 14, 2018
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9
Oncology & Cancer
Precancerous colon polyps in patients with Lynch syndrome exhibit immune activation
Colon polyps from patients with Lynch syndrome, a hereditary condition that raises colorectal cancer risk, display immune system activation well before cancer development, according to research from The University of Texas ...
Apr 16, 2018
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62
Oncology & Cancer
Accurately diagnosing genetic disease prevents cancer, saves lives
A single, upfront genomic test is more effective for detecting Lynch syndrome in colorectal cancer (CRC) patients than the traditional multiple, sequential testing approach, according to new clinical data reported by The ...
Mar 29, 2018
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211
Genetics
Two new breast cancer genes emerge from Lynch syndrome gene study
Researchers at Columbia University Irving Medical Center and NewYork-Presbyterian have identified two new breast cancer genes. Having one of the genes—MSH6 and PMS2—approximately doubles a woman's risk of developing breast ...
Jan 18, 2018
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837
Genetics
Increasing the age limit for Lynch syndrome genetic testing may save lives
Raising the age limit for routine genetic testing in colorectal cancer could identify more cases of families affected by Lynch syndrome, a condition that accounts for around 5% of all colon cancers, according to new research ...
May 29, 2017
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