Other
The painful side of positive health care marketing
Lori Wallace sits on a couch with her 11-year-old son and his new pet snake. It burrows under his armpit, as if afraid. Wallace is sure it's not.
Oct 30, 2017
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Metastatic Breast Cancer
Oncology & Cancer
Cholesterol byproduct hijacks immune cells, lets breast cancer spread
High cholesterol levels have been associated with breast cancer spreading to other sites in the body, but doctors and researchers don't know the cause for the link. A new study by University of Illinois researchers found ...
Oct 12, 2017
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709
Oncology & Cancer
Abemaciclib initial therapy improves outcome in endocrine-sensitive advanced breast cancer
The results of the MONARCH 3 trial, presented at the ESMO 2017 Congress in Madrid, showed that adding the cyclin-dependent kinase (CDK) 4/6 inhibitor abemaciclib to endocrine therapy improved progression-free survival compared ...
Sep 11, 2017
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1
Oncology & Cancer
LORELEI: Taselisib boosts breast tumor shrinkage
Adding taselisib to letrozole before surgery significantly improved outcomes for patients with early breast cancer that was both estrogen receptor positive and HER2-negative (ER+/HER2-) according to results of the LORELEI ...
Sep 8, 2017
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1
Medications
Non-psychotropic cannabinoids show promise for pain relief
Some cancers love bone. They thrive in its nutrient-rich environment while gnawing away at the very substrate that sustains them, all the while releasing inflammatory substances that cause pain—pain so severe that opioids ...
Sep 4, 2017
2
1011
Oncology & Cancer
Z-endoxifen shows promise as new treatment for common breast cancer type
Z-endoxifen, a potent derivative of the drug tamoxifen, could itself be a new treatment for the most common form of breast cancer in women with metastatic disease. This finding was reported from a clinical trial conducted ...
Aug 31, 2017
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12
Oncology & Cancer
Cell cycle-blocking drugs can shrink tumors by enlisting immune system in attack on cancer
In the brief time that drugs known as CDK4/6 inhibitors have been approved for the treatment of metastatic breast cancer, doctors have made a startling observation: in certain patients, the drugs—designed to halt cancer ...
Aug 16, 2017
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61
Oncology & Cancer
Genome sequencing method can detect clinically relevant mutations using five CTCs
Whole genome sequencing using long fragment read (LFR), a technology that can analyze the entire genomic content of small numbers of cells, detected potentially targetable mutations using only five circulating tumor cells ...
Aug 15, 2017
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2
Oncology & Cancer
New study reveals late spread of breast cancer and backs key role of early diagnosis
Breast cancer cells that spread to other parts of the body break off and leave the primary tumour at late stages of disease development, scientists from the Wellcome Trust Sanger Institute and their collaborators have found.
Aug 14, 2017
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93
Oncology & Cancer
A new HER2 mutation, a clinical trial and a promising diagnostic tool for metastatic breast cancer
There is a group of metastatic breast cancers that has the HER2 gene amplified - the cells have many copies of it - which leads to enhanced activity of the product enzyme, a tyrosine kinase. HER2 has been established as a ...
Aug 1, 2017
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