Immunology
Betrayed by bile ducts? Researchers look for clues to treating a mysterious autoimmune disease
Your bile duct network is a true tree of life. A floppy, pink tree of life.
May 15, 2025
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Myasthenia Gravis
Immunology
Traditional Chinese medicine formula shows promise for myasthenia gravis treatment
Myasthenia gravis (MG) is a rare, chronic autoimmune disorder that disrupts the communication between nerves and muscles. It typically leads to symptoms such as muscle weakness, drooping eyelids, difficulty swallowing, fatigue, ...
May 13, 2025
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Medications
FDA approves self-injection of Vyvgart Hytrulo
The U.S. Food and Drug Administration has approved a self-injection version of Vyvgart Hytrulo (efgartigimod alfa and hyaluronidase-qvfc) for the treatment of adult patients with generalized myasthenia gravis (gMG) who are ...
Apr 16, 2025
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Diseases, Conditions, Syndromes
Advanced imaging reveals mechanisms that cause autoimmune disease
People who suffer from the autoimmune disease myasthenia gravis experience muscle weakness that can affect any of the muscles we use to blink, smile or even move our body around.
Apr 8, 2025
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Genetics
Urine test offers simpler diagnosis for mitochondrial disorders, study finds
New research at the University of Alberta may make it easier to diagnose serious diseases that disrupt the body's energy supply.
Feb 11, 2025
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Neuroscience
Harnessing the brain power behind speech to help detect neurodegenerative disease
There's a lot of brain power that goes into speech. First, there's a thought or idea, which the brain must translate into words. Those words are then translated into specific movements of the lungs, tongue and mouth to shape ...
Jan 15, 2025
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Diseases, Conditions, Syndromes
Research highlights enzyme's therapeutic potential in managing immune-related disorders
Myasthenia gravis (MG) is a chronic autoimmune disorder in which antibodies block communication between nerves and muscle, resulting in weakness of the skeletal muscles. It can cause double vision, difficulty swallowing, ...
Oct 21, 2024
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Surgery
Benefits of thymectomy in treating myasthenia gravis
The first-ever randomized study of the removal of the thymus gland in treating myasthenia gravis was conducted in 2016. Led by Gil I. Wolfe, MD, SUNY Distinguished Professor and the Irvin and Rosemary Smith Professor of Neurology ...
Jul 2, 2024
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Obstetrics & gynaecology
Rheumatic diseases associated with childbearing problems
A new paper in Rheumatology finds that rheumatic diseases can lead to reproductive problems, though some conditions have more detrimental effects than others.
Mar 20, 2024
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Health
This is how tobacco damages our cells
My father smoked a pipe for some time, and I vividly remember that sticky black substance—tar—which stuck to the device's filter. Now imagine this stuff going into your lungs, and coating their walls. The picture is unpleasant, ...
Feb 12, 2024
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Myasthenia gravis (from Greek μύς "muscle", ἀσθένεια "weakness", and Latin: gravis "serious"; abbreviated MG) is an autoimmune neuromuscular disease leading to fluctuating muscle weakness and fatiguability. It is an autoimmune disorder, in which weakness is caused by circulating antibodies that block acetylcholine receptors at the postsynaptic neuromuscular junction, inhibiting the excitatory effects of the neurotransmitter acetylcholine on nicotinic receptors throughout neuromuscular junctions. Myasthenia is treated medically with cholinesterase inhibitors or immunosuppressants, and, in selected cases, thymectomy. The disease incidence is 3–30 cases per million per year and rising as a result of increased awareness. MG must be distinguished from congenital myasthenic syndromes that can present similar symptoms but offer no response to immunosuppressive treatments.
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