Myasthenia gravis (MG) is a chronic autoimmune disorder in which antibodies block communication between nerves and muscle, resulting in weakness of the skeletal muscles. It can cause double vision, difficulty swallowing, ...
Oct 21, 2024
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The first-ever randomized study of the removal of the thymus gland in treating myasthenia gravis was conducted in 2016. Led by Gil I. Wolfe, MD, SUNY Distinguished Professor and the Irvin and Rosemary Smith Professor of Neurology ...
Jul 2, 2024
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A new paper in Rheumatology finds that rheumatic diseases can lead to reproductive problems, though some conditions have more detrimental effects than others.
Mar 20, 2024
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My father smoked a pipe for some time, and I vividly remember that sticky black substance—tar—which stuck to the device's filter. Now imagine this stuff going into your lungs, and coating their walls. The picture is unpleasant, ...
Feb 12, 2024
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A University of Alberta team has uncovered a universal biological marker for myasthenia gravis with the aim of developing a simple, fast and accessible diagnostic test for the rare autoimmune disease.
Jan 16, 2024
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The U.S. Food and Drug Administration has approved UCB' Zilbrysq (zilucoplan) for the treatment of adults with generalized myasthenia gravis.
Oct 25, 2023
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The U.S. Food and Drug Administration has approved Vyvgart Hytrulo (efgartigimod alfa and hyaluronidase-qvfc) subcutaneous injections for the treatment of generalized myasthenia gravis (gMG) in adult patients who are anti-acetylcholine ...
Jun 28, 2023
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A significant proportion of patients who survive COVID-19 develop a constellation of life-altering symptoms that persist long after the initial infection has resolved. This post-COVID-19 syndrome may result from the development ...
Jun 27, 2023
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Evidence from a small-scale clinical trial suggests that a variation of the advanced blood cancer immunotherapy known as CAR-T could be adapted to treat myasthenia gravis, an autoimmune disorder of the nervous system. The ...
Jun 22, 2023
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The Lancet Neurology has published data from the phase 3 MycarinG study evaluating the efficacy and safety of rozanolixizumab in adult patients with acetylcholine receptor autoantibody-positive (AChR-Ab+) or muscle-specific ...
Apr 13, 2023
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Myasthenia gravis (from Greek μύς "muscle", ἀσθένεια "weakness", and Latin: gravis "serious"; abbreviated MG) is an autoimmune neuromuscular disease leading to fluctuating muscle weakness and fatiguability. It is an autoimmune disorder, in which weakness is caused by circulating antibodies that block acetylcholine receptors at the postsynaptic neuromuscular junction, inhibiting the excitatory effects of the neurotransmitter acetylcholine on nicotinic receptors throughout neuromuscular junctions. Myasthenia is treated medically with cholinesterase inhibitors or immunosuppressants, and, in selected cases, thymectomy. The disease incidence is 3–30 cases per million per year and rising as a result of increased awareness. MG must be distinguished from congenital myasthenic syndromes that can present similar symptoms but offer no response to immunosuppressive treatments.
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