Clonal hematopoiesis (CH) is a recently characterized condition in which the genetic mutations associated with leukemia and other blood cancers are found in the blood of individuals without cancer. This pre-cancerous state ...
Dec 13, 2022
0
8
New research published in Science Advances today conducted by researchers at Peter MacCallum Cancer Center show a new treatment for two challenging blood cancers could potentially help more patients than originally thought.
Sep 15, 2022
0
38
Hypomethylating agents (HMA) are currently used as a first-line treatment for patients with myelodysplastic syndrome (MDS), and increasingly in other diseases, but their mechanism of action is not clear. HMAs may affect many ...
May 26, 2022
0
18
Cancer patients actively receiving systemic anticancer treatment (SACT) who become infected with COVID-19 do not experience higher COVID-19 mortality, according to a study published online Feb. 21 in JAMA Network Open.
Feb 28, 2022
0
2
Mount Sinai and UC San Diego researchers have shown for the first time how mutations affecting a cellular process called RNA splicing alter cells to develop myelodysplastic syndrome (MDS) and other hematologic malignancies ...
Oct 7, 2021
0
21
The chemotherapy drug decitabine is commonly used to treat patients with blood cancers, but its response rate is somewhat low. Researchers have now identified why this is the case, opening the door to more personalized cancer ...
May 24, 2021
0
14
Myelodysplastic syndrome (MDS) is a disease of the stem cells in the bone marrow, which disturbs the maturing and differentiation of blood cells. Annually, some 200 Finns are diagnosed with MDS, which can develop into acute ...
Mar 22, 2021
0
8
A clinical trial of a new gene therapy for sickle cell disease that has shown promise has been halted after two participants were diagnosed with cancer.
Feb 24, 2021
0
1
A research team led by the Icahn School of Medicine at Mount Sinai (Icahn Mount Sinai) has built the first cellular model to depict the evolution of acute myeloid leukemia (AML), from its early to late stages. By using gene ...
Feb 10, 2021
0
50
Sophia Ceder and Klas Wiman and their colleagues at Department of Oncology-Pathology have together with researchers from Peter MacCallum Cancer Center, University of Melbourne, University of Cambridge and Aprea Therapeutics ...
Dec 18, 2020
0
33
