Glioblastoma, one of the most aggressive and lethal brain cancers, has a five-year survival rate of only 6.9%, according to the National Brain Tumor Society. While the relationship between glioblastoma and cell death, also ...
Mar 27, 2025
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In a clinical guideline issued by the American College of Gastroenterology and published online in the March issue of the American Journal of Gastroenterology, evidence-based recommendations are presented for the management ...
Mar 19, 2024
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In an expert consensus statement published online Oct. 28 in the Canadian Journal of Cardiology, the authors present the classification of four stages of myocardial infarction (MI) based on myocardial tissue injury, culminating ...
Nov 6, 2023
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What happens when the blood supply to your bones is somehow damaged?
May 31, 2023
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A tumor's necrotic core contains factors that appear to promote metastasis, or the seeding of tumors cells throughout the body, according to a new study in rats by researchers at Fred Hutchinson Cancer Center.
Feb 28, 2023
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Just as people keep their houses clean and clutter under control, a crew of cells in the body is in charge of clearing the waste the body generates, including dying cells. The housekeeping cells remove unwanted material by ...
May 6, 2021
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White blood cells are part of many immune system responses in the human body. New research shows that a specific type of those cells may cause brain cancer tissues to die—but that's not good news, according to researchers ...
Dec 7, 2020
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Alzheimer's remains the leading cause of dementia in Western societies, with some estimates suggesting that as many as 24 million people worldwide are living with the disease. Alzheimer's is characterized by a progressive ...
Feb 13, 2020
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Each year, heart attacks kill almost 10 million people around the world, and more than 6 million die from stroke. A heart attack is caused by clots that block arterial blood flow. Tissues are deprived from blood-borne oxygen. ...
Oct 15, 2019
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(HealthDay)—Myocardial necrosis is common after orthopedic surgery and is associated with increased risk of long-term mortality, according to a study published in the June 15 issue of The American Journal of Cardiology.
Jun 3, 2015
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Necrosis (from the Greek νεκρός, "dead", νέκρωσις, "death, the stage of dying, the act of killing") is the premature death of cells in living tissue. Necrosis is caused by factors external to the cell or tissue, such as infection, toxins, or trauma. This is in contrast to apoptosis, which is a naturally occurring cause of cellular death. While apoptosis often provides beneficial effects to the organism, necrosis is almost always detrimental and can be fatal.
Cells that die due to necrosis do not usually send the same chemical signals to the immune system that cells undergoing apoptosis do. This prevents nearby phagocytes from locating and engulfing the dead cells, leading to a build-up of dead tissue and cell debris at or near the site of the cell death. For this reason, it is often necessary to remove necrotic tissue surgically, a process known as debridement.
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