Genetics

Gene therapy blocks peripheral nerve damage in mice

Nerve axons serve as the wiring of the nervous system, sending electrical signals that control movement and sense of touch. When axons are damaged, whether by injury or as a side effect of certain drugs, a program is triggered ...

Neuroscience

Scientist identifies mechanism underlying peripheral neuropathy

Recent research by Sandra Rieger, Ph.D., of the MDI Biological Laboratory identifying the underlying mechanisms of peripheral neuropathy, or nerve damage, has raised the prospect that drug therapies can be developed for the ...

Medical research

How a mutated gene wreaks havoc on white matter

An inherited disease of myelin marked by slow, progressive neurological impairment is caused by mutations of a gene that controls lipid metabolism, a finding that may shed insight into mechanisms to control the course of ...

Medical research

Study identifies unexpected clue to peripheral neuropathies

New research shows that disrupting the molecular function of a tumor suppressor causes improper formation of a protective insulating sheath on peripheral nerves – leading to neuropathy and muscle wasting in mice similar ...

Diseases, Conditions, Syndromes

Key risk factors for diabetic foot reinfections uncovered in study

Texas has one of the highest rates of diabetes in the country, with more than 2.7 million Texans diagnosed with the condition. About one in six people in San Antonio have type 2 diabetes, and a third of residents are prediabetic, ...

Oncology & Cancer

Cancer drugs cause chronic peripheral nerve pain in 40% of patients

Worldwide, cancer chemotherapy is linked to persistent severe peripheral nerve pain (neuropathy) for around four in every 10 patients treated with these drugs, suggests a pooled data analysis of the available evidence, published ...

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