A team of scientists who a few years ago identified a major pathway that leads to brain cell death in mice, have now found two drugs that block the pathway and prevent neurodegeneration. The drugs caused minimal side effects ...
Apr 20, 2017
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Fresh insights into infectious brain conditions help to explain why some people - and animals - are more at risk than others.
Dec 14, 2016
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Wildlife disease experts at Colorado State University are investigating whether a test developed to detect early-stage chronic wasting disease in deer might also be used to identify the onset of brain disorders, including ...
Dec 13, 2016
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(HealthDay)—Cerebrospinal fluid (CSF) real-time quaking-induced conversion (RT-QuIC) has high diagnostic specificity and sensitivity for prion diseases, according to a study published online Nov. 28 in the Annals of Neurology.
Dec 3, 2016
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Prions are misfolded proteins. The complex three-dimensional structure of a prion's progenitor protein becomes altered, somehow causing it to malfunction. Worse, the malformation of these progenitor proteins into prions causes ...
Nov 30, 2016
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For the first time, scientists have isolated a mutated prion protein that can multiply in the lab but not in living animals, according to a PLOS Pathogens study. The mutant prion provides new insights into the mechanisms ...
Nov 23, 2016
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A new model of fatal brain diseases is being developed in the fruit fly by a team led by Dr Raymond Bujdoso at the University of Cambridge, and could lead to a low cost, fast and efficient blood test to diagnose - and prevent ...
Oct 13, 2016
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Prion diseases are deadly neurodegenerative disorders in humans and animals that are characterized by misfolded forms of prion protein (PrP). Development of effective treatments has been hampered by the lack of good experimental ...
Aug 9, 2016
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Prion diseases are fatal and incurable neurodegenerative conditions of humans and animals. Yet, how prions kill nerve cells (or neurons) remains unclear. A study published on May 26, 2016 in PLOS Pathogens describes a system ...
May 26, 2016
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Transmissible spongiform encephalopathies (TSEs), or prion diseases, are a family of rare progressive, neurodegenerative illnesses that affect both humans and animals. TSE surveillance is important for public health and food ...
Apr 8, 2016
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