A study led by the University of Utah School of Medicine provides new insights into how the subtle changes within cells, caused by disruptions in a gene called Kirrel3, could underlie some types of intellectual disability ...
Nov 17, 2015
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Deep brain stimulation – usually used to treat movement disorders – overcomes the learning and memory deficits in mice whose symptoms mimic those of Rett syndrome, a neurological disease usually found in young girls, ...
Oct 14, 2015
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Using "mini-brains" built with induced pluripotent stem cells derived from patients with a rare, but devastating, neurological disorder, researchers at University of California, San Diego School of Medicine say they have ...
Sep 8, 2015
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A team at Cold Spring Harbor Laboratory (CSHL) has developed a strikingly new approach for treating Rett syndrome, a devastating autism spectrum disorder (ASD) that affects 1 in 10,000 people in the US, mostly girls. In a ...
Jul 27, 2015
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The term intellectual disability covers a large number of clinical entities, some with known cause and others of uncertain origin. For example Down syndrome is due to an extra copy of chromosome 21 and Rett syndrome is in ...
Jul 20, 2015
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Independent reproduction of other scientists' results is a cornerstone of solid research, but scientists are rarely recognized for successfully reproducing published findings, much less for demonstrating that scientific findings ...
May 20, 2015
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New research by investigators at the University of Massachusetts Medical School suggests the immune system plays an unsuspected and surprising role in the progression of Rett syndrome, a severe neurological disorder affecting ...
May 11, 2015
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The immune system is designed to protect us from disease. But what if it was malfunctioning? Would it make a disease worse? That appears to be the case with Rett syndrome, a neurodevelopmental disorder, and possibly in other ...
Apr 21, 2015
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Mutations in the methyl CpG binding protein 2 gene (MECP2) are the cause of the devastating childhood neurological disorder Rett Syndrome. Despite intense efforts spanning several decades the precise function of MECP2 has ...
Mar 11, 2015
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With the help of mouse models, induced pluripotent stem cells (iPSCs) and the "tooth fairy," researchers at the University of California, San Diego School of Medicine have implicated a new gene in idiopathic or non-syndromic ...
Nov 11, 2014
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