Oncology & Cancer

New tumor models provide insights into deadly sarcomas

Sarcomas are highly metastatic soft tissue and bone cancers and are often difficult to treat. Scientists have had trouble studying these cancers because they have lacked good research models. But that may be changing, thanks ...

Oncology & Cancer

FDA approves engineered cell therapy for treating rare sarcoma

The U.S. Food and Drug Administration (FDA) has granted accelerated approval for the immunotherapy afamitresgene autoleuecel (Tecelra, also known as afami-cel) for the treatment of adults with a rare soft tissue cancer called ...

Oncology & Cancer

The roles of USP1 in Ewing sarcoma

A new research paper titled "Roles of USP1 in Ewing sarcoma" has been published in Genes & Cancer.

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A sarcoma (from the Greek sarx (σάρκα) meaning "flesh") is a cancer that arises from transformed cells of mesenchymal origin. Thus, malignant tumors made of cancerous bone, cartilage, fat, muscle, vascular, or hematopoietic tissues are, by definition, considered sarcomas. This is in contrast to a malignant tumor originating from epithelial cells, which are termed carcinoma. Sarcomas are quite rare - common malignancies, such as breast, colon, and lung cancer, are almost always carcinoma.

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