Oncology & Cancer

Possible new treatment for Ewing sarcoma

Discovery of a new drug with high potential to treat Ewing sarcoma, an often deadly cancer of children and young adults, and the previously unknown mechanism behind it, come hand-in-hand in a new study by researchers from ...

Oncology & Cancer

New drug overcomes resistance in patients with rare sarcoma

A new targeted drug demonstrated its ability to control metastatic gastrointestinal stromal tumor, an uncommon and life-threatening form of sarcoma, after the disease had become resistant to all existing therapies, report ...

Oncology & Cancer

More intensive chemo ups survival in ewing sarcoma

(HealthDay)—More intensive chemotherapy (every two weeks versus every three weeks) improves event-free survival for patients with localized Ewing sarcoma, according to a study published online Oct. 22 in the Journal of ...

Oncology & Cancer

Sugar-free approach to treating Kaposi sarcoma

A sugar-loving protein drives the growth of Kaposi sarcoma (KS) tumors, according to a study published on October 1st in The Journal of Experimental Medicine. Interfering with these sugary interactions inhibited growth of ...

Oncology & Cancer

New marker, new target in Ewing's sarcoma

Ewing's sarcoma is a bone cancer commonly diagnosed in about 250 U.S. teenagers per year. If early chemotherapy is effective, improvement can be durable. But for children and teens who respond poorly to a first attempt at ...

Oncology & Cancer

Researchers identify drivers of sarcoma growth and survival

To better understand the signaling pathways active in sarcomas, researchers at Moffitt Cancer Center used state-of-the-art mass spectrometry-based proteomics to characterize a family of protein enzymes that act as "on" or ...

Oncology & Cancer

Bevacizumab active in HIV-linked Kaposi's sarcoma

(HealthDay) -- For patients with HIV-associated Kaposi's sarcoma (HIV-KS), bevacizumab is tolerated and induces a response in some patients, according to a study published online March 19 in the Journal of Clinical Oncology.

Medications

3Qs: Analyzing why sudden drug shortages occur

Drug manufacturers and the Food and Drug Administration (FDA) scrambled earlier this month to address a sudden shortage of methotrexate, a 60-year-old drug that treats children with severe cases of leukemia and sarcoma. Graham ...

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