Diseases, Conditions, Syndromes

Heartburn drugs again tied to fatal risks

(HealthDay)—People who use common heartburn drugs for months to years may face heightened risks of dying from heart disease, kidney failure or stomach cancer, a new study suggests.

Oncology & Cancer

Pathogens find safe harbor deep in the gastric glands

Scientists have long tried to understand how pathogenic bacteria like Helicobacter pylori, a risk factor for stomach ulcers and cancer, survive in the harsh environment of the stomach. In a new study publishing May 2 in the ...

Oncology & Cancer

Study shows why stomach pathogen is so tough to eradicate

The stomach-dwelling bacteria Helicobacter pylori survives in the stomach—a hellish, churning vat of hydrochloric acid—by holing up inside that organ's pitlike glands and establishing squatter's rights. Once the germ ...

Gerontology & Geriatrics

The effect of sleep quality on peptic-ulcer relapse in older adults

Poor sleep quality and peptic ulcer disease (PUD, a condition when sores known as ulcers develop on the lining of your stomach or in the first part of your small intestine) are both major public health problems that affect ...

Medical research

New study explains how inflammation causes gastric cancer

In 1982, researchers reported a link between chronic gastritis and stomach bacterium Helicobacter pylori, triggering a flurry of research into this newly identified pathogen. These studies made it clear that in addition to ...

Medical research

Bacteria play only a minor role stomach ulcers in cattle

Scientists at the University of Veterinary Medicine Vienna investigated whether stomach ulcers in cattle are related to the presence of certain bacteria. For their study, they analysed bacteria present in healthy and ulcerated ...

Medical research

Glutamine supplements show promise in treating stomach ulcers

Nearly 20 years ago, it was discovered that bacteria known as Helicobacter pylori were responsible for stomach ulcers. Since then, antibiotics have become the primary therapy used to combat the H. pylori infection, which ...

Diseases, Conditions, Syndromes

Simple measures may prevent transmission of stomach ulcer bacteria

The stomach ulcer bacterium Helicobacter pylori is not transmitted through drinking water as previously thought, but rather through vomit and possibly faeces. This is shown in a thesis at the Sahlgrenska Academy, University ...

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A peptic ulcer, also known as PUD or peptic ulcer disease, is the most common ulcer of an area of the gastrointestinal tract that is usually acidic and thus extremely painful. It is defined as mucosal erosions equal to or greater than 0.5 cm. As many as 70–90% of such ulcers are associated with Helicobacter pylori, a spiral-shaped bacterium that lives in the acidic environment of the stomach; however, only 40% of those cases go to a doctor. Ulcers can also be caused or worsened by drugs such as aspirin, ibuprofen, and other NSAIDs.

Four times as many peptic ulcers arise in the duodenum—the first part of the small intestine, just after the stomach—as in the stomach itself. About 4% of stomach ulcers are caused by a malignant tumor, so multiple biopsies are needed to exclude cancer. Duodenal ulcers are generally benign.

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