Hypoxic-ischemic encephalopathy (HIE) is one of the leading causes of newborn mortality and morbidity worldwide, and lowering the baby's body temperature—called therapeutic hypothermia—is often used as a treatment.
Nov 20, 2024
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Treatments to help babies who run out of oxygen during pregnancy or at birth (neonatal encephalopathy) are limited. Therapeutic hypothermia is the only option used to prevent brain damage in such cases, but 29% of babies ...
Feb 15, 2024
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Delivering critical early-life medication to newborns at risk of cerebral palsy from suspected brain injury will be safer thanks to a University of Alberta research team.
Feb 15, 2024
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Hypoxic-ischemic encephalopathy (HIE), brain injury caused by oxygen deprivation around birth, is a common cause of admission to the neonatal intensive care unit. Therapeutic hypothermia is now becoming the standard treatment ...
Aug 31, 2023
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Therapeutic hypothermia is a well-established therapy with clear neuroprotective effects. It has been widely used in cases of neonatal hypoxic encephalopathy and cardiac arrest. Researchers have been attempting to apply therapeutic ...
Jul 10, 2023
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Therapeutic hypothermia, the only evidence-based treatment for newborns born with neonatal encephalopathy (NE) at or after 36 weeks, is not effective for reducing death or moderate/severe disability in newborns born between ...
Apr 28, 2023
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For brain-dead organ donors, therapeutic hypothermia is inferior to machine perfusion of the kidneys for reducing delayed graft function after transplantation, according to a study published in the Feb. 2 issue of the New ...
Feb 2, 2023
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Adding erythropoietin to cooling therapy for term newborns with birth asphyxia has no benefit over cooling therapy alone, a study published today in the New England Journal of Medicine.
Jul 14, 2022
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In patients receiving therapeutic hypothermia after suffering out-of-hospital cardiac arrest, those who were cooled below 31 degrees Celsius (about 88 degrees Fahrenheit) for 24 hours showed no difference in terms of death ...
May 17, 2021
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A tenth of all intensive care unit patients worldwide, and many critical patients with COVID-19, have acute respiratory distress syndrome (ARDS). Therapeutic hypothermia, an intentional cooling of the body, has been suggested ...
Feb 23, 2021
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Therapeutic hypothermia, also known as protective hypothermia, is a medical treatment that lowers a patient's body temperature in order to help reduce the risk of the ischemic injury to tissue following a period of insufficient blood flow. Periods of insufficient blood flow may be due to cardiac arrest or the occlusion of an artery by an embolism, as occurs in the case of strokes. Therapeutic hypothermia may be induced by invasive means, in which a catheter is placed in the inferior vena cava via the femoral vein, or by non-invasive means, usually involving a chilled water blanket or torso vest and leg wraps in direct contact with the patient's skin. Studies have demonstrated that patients at risk for ischemic brain injuries have better outcomes if treated with a hypothermia protocol.
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