Genetics

What role do genome variations play in tuberculosis?

Tuberculosis is caused by Mycobacterium tuberculosis. In 2016, this was the most common causative pathogen for death by infectious diseases. Therefore, investigating the biology of infection and disease development is important ...

Diseases, Conditions, Syndromes

Tuberculosis drug may work better than others in its class

Treatment of tuberculosis involves a combination of several drugs, sometimes including drugs from a class known as fluoroquinolones. Using computer simulations, scientists have shown that the fluoroquinolone known as moxifloxacin ...

Diseases, Conditions, Syndromes

Change in conversion definition may improve TB detection

(HealthDay)—A change of QuantiFERON-TB interferon (IFN)γ values from 0.7 IU/mL is associated with an increased incidence in the rate of tuberculosis, according to a study published online July 24 in the American Journal ...

Diseases, Conditions, Syndromes

A genetic variation may increase tuberculosis susceptibility

Researchers have shown that a single nucleotide change in a gene that affects production of hepcidin—a peptide involved in inflammation, immunity, and control of iron levels—is associated with greater susceptibility to ...

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