Most tumors release various signaling molecules to support their incessant growth, invasion, and metastasis. Some of these molecules, known as tumor angiogenic factors (TAF), are able to stimulate the formation of new blood ...
Aug 9, 2024
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The complex interplay between extracellular genetic material and the tumor's genetic landscape presents a significant challenge in grasping cancer evolution, tumor genetic heterogeneity, and treatment response. Earlier research ...
Aug 9, 2024
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Progenitor exhausted CD8+ T (Tpex) cells have emerged as a pivotal component in tumor immunotherapy due to their unique ability to self-renew and rapidly proliferate. These cells have shown promise in expanding and differentiating ...
Aug 8, 2024
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A drug effective in treating breast cancer shows new promise in addressing breast cancer with brain metastases or recurrent glioblastoma, as reported by results of a prospective window-of-opportunity trial at the University ...
Aug 8, 2024
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Using a unique collection of genetic and clinical data for colorectal cancer, researchers at Uppsala University have revealed genetic new alterations and developed of a new molecular classifier of tumor variants. The finding ...
Aug 7, 2024
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Cancer doesn't grow in a vacuum—each tumor grows in a particular microenvironment within the body and spreads through a tangled web of vasculature and nerves. Scientists have come to understand that the most potent therapies ...
Aug 7, 2024
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Glioblastoma multiforme (GBM) stands as a formidable adversary in oncology, characterized by its molecular complexity and relentless progression. Despite advancements, the high degree of tumor heterogeneity and its tendency ...
Aug 7, 2024
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By recruiting the immune system to combat tumor cells, immunotherapy has improved survival rates, offering hope to millions of cancer patients. However, only about one in five people responds favorably to these treatments.
Aug 6, 2024
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Yu-Hwa Huang, Ph.D. and Charles Yoon, MD, of the Department of Medicine and Department of Surgery at Brigham and Women's Hospital respectively, are co-lead authors of a paper titled "High-dimensional mapping of human CEACAM1 ...
Aug 6, 2024
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A protein called Meteorin-like (METRNL) in the tumor microenvironment saps energy from T cells, thereby severely limiting their ability to fight cancer, according to new research directed by investigators at the Johns Hopkins ...
Aug 6, 2024
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